EUGENOL

PRODUCT IDENTIFICATION

CAS NO. 97-53-0

EUGENOL

EINECS NO. 202-589-1
FORMULA CH2CH2CH2C6H3(OCH3)OH
MOL WT. 164.20

H.S. CODE

2909.50.4010

TOXICITY

Oral rat LD50: 2680 mg/kg
SYNONYMS

Eugenol ; Eugenic acid; p-Allylguaiacol; p-Eugenol;  

2-Methoxy-4-(2-propenyl)phenol; Allylguaiacol; 1,3,4-Eugenol; 1-Hydroxy-2-methoxy-4-allylbenzene; 1-Hydroxy-2-methoxy-4-prop-2-enylbenzene; 1-Hydroxy-2-methoxy-4-propenylbenzene; 2-Methoxy-1-hydroxy-4-allylbenzene; 2-Methoxy-4-(2-propen-1-yl)phenol; 2-Methoxy-4-allylphenol; 2-Methoxy-4-prop-2-enylphenol; 2-Metoksy-4-allilofenol; 4-Allyl-1-hydroxy-2-methoxybenzene; 4-Allyl-2-methoxyphenol; 4-Allylcatechol 2-methyl ether; 4-Allylcatechol-2-methyl ether; 4-Allylguaiacol; 4-Hydroxy-3-methoxy-1-allylbenzene; 4-Hydroxy-3-methoxyallylbenzene; 5-Allylguaiacol; Allylguaiacol; Caryophyllic acid;

SMILES c1(cc(ccc1O)CC=C)OC

CLASSIFICATION

Analgesic, Anti-Infective, Insect attractant, repellent and chemosterilant

EXTRA NOTES

FEMA No. 2467
Overall Carcinogenic Evaluation: Group 3
A cinnamate derivative of the shikamate pathway found in clove oil and other plants.
EPA Pesticide Chemical Code 102701 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE clear to pale yellow oily liquid

MELTING POINT

-9 C
BOILING POINT 254 C
SPECIFIC GRAVITY 1.06

SOLUBILITY IN WATER

<1 mg/ml

SOLVENT SOLUBILITY

Miscible with alcohol, ether, Chloroform; Soluble in acetic acid, alkali hydroxide solutions
pH  
VAPOR DENSITY  

AUTOIGNITION

 

NFPA RATINGS

Health: 2; Flammability: 1; Reactivity: 0

REFRACTIVE INDEX

1.5410
FLASH POINT

> 104 C

STABILITY Stable under ordinary conditions. Light sensitive

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - Eugenol

PubChem Compound Summary - Eugenol

IPCS INCHEM -  Eugenol

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Eugenol

http://www.ebi.ac.uk/chebi/ -  Eugenol

http://www.ncbi.nlm.nih.gov/ -  Eugenol

Human Metabolome Database - Eugenol

Material Safety Data Sheet

http://www.thegoodscentscompany.com/ - Eugenol

http://www.indepthinfo.com/
Eugenol is an allyl chain-substituted guaiacol (2-methoxyphenol). It appears as a clear or pale yellow oily liquid. Besides cloves, it can also be extracted from cinnamon and other aromatic spices. It is slightly soluble in water and soluble in organic solvents. The medical field makes use of Eugenol. Its properties make it a good local antiseptic and analgesic. It is used in dentist offices to make
zinc-oxide eugenol paste for temporary fillings2. It also makes a good local anaesthetic for temporary relief from toothache pain3. It is used in the production of isoeugenol for the manufacture of vanillin which is an artificial substitute for vanilla.

Local:
Eugenol, allyl chain-substituted guaiacol (2-methoxyphenol), is a clear to pale yellow oily liquid extracted from certain essential oils especially from clove oil and cinnamon. It is very slightly soluble in water and soluble in organic solvents. It has a spicy odor and taste of clove. Eugenol is used in perfumeries, flavorings, essential oils and in medicine (local antiseptic and analgesic). It is used in the production of isoeugenol for the manufacture of vanillin. Eugenol has wide application in dentistry for analgesic and antiseptic properties. Eugenol derivatives or methoxyphenol derivatives in wider classification are used in perfumery and flavoring. They are used in formulating insect attractants and UV absorbers, analgesics, biocides and antiseptics. They are also used in manufacturing stabilizers and antioxidants for plastics and rubbers.

SALES SPECIFICATION

APPEARANCE

pale yellow liquid

ASSAY

98.0% min

REFRACTIVE INDEX

1.540 - 1.542
SPECIFIC GRAVITY 1.065 - 1.07
TRANSPORTATION
PACKING  
HAZARD CLASS  
UN NO. Not regulated
SAFETY INFORMATION

HAZARD OVERVIEW

OSHA Hazards: Target Organ Effect, Harmful by ingestion., Corrosive. May cause allergic skin reaction. Air sensitive. May be harmful if swallowed. Causes eye, skin, and respiratory tract irritation. Target Organs: Kidney, Central nervous system, Lungs, Gastrointestinal tract, skin.

GHS

 

SIGNAL WORD Warning

PICTOGRAMS

HAZARD STATEMENTS

H302 Harmful if swallowed.
H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H335 May cause respiratory irritation.
H402 Harmful to aquatic life.

PRECAUTIONARY  STATEMENTS

P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P280 Wear protective gloves.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER or doctor/ physician.

EC DIRECTIVES

 

HAZARD CODES

Xn Harmful

RISK PHRASES

22 Harmful if swallowed
36/37/38
Irritating to eyes, respiratory system and skin
42/43
May cause sensitization by inhalation and skin contact

SAFETY PHRASES

26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36
Wear suitable protective clothing

PRICE INFORMATION