D-PROLINOL

PRODUCT IDENTIFICATION

CAS NO 68832-13-3

D-PROLINOL

EINECS NO.

 

FORMULA C5H11NO
MOL WT. 101.15

H.S. CODE

TOXICITY

SYNONYMS (R)-(-)-2-(Hydroxymethyl)pyrrolidine;
D-(-)Prolinol; (R)-(-)-2-Hydroxymethylpyrrolidine; (R)-(-)-2-Pyrrolidinemethanol;
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE clear to yellow  liquid
MELTING POINT  
BOILING POINT 74 - 76 C at 2 mm Hg
SPECIFIC GRAVITY

1.025

SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

 

AUTOIGNITION

 

FLASH POINT

 

STABILITY Stable under ordinary conditions. Hygroscopic

APPLICATIONS

Chiral amino alcohol possessing both amine and alcohol is a structural motif for the compounds which have important biological and pharmacological functions within the body as inhibitor of aspartyl proteases, aldose reductase, b-amyloid peptide formation, and dopamine D4 antagonists. The chiral amino alcohol also exhibits anti-inflammatory, anesthetic, antipasmodic, hepatotoxic, anti-diabetic, anti-obesity,and anti-depressant activities. Chiral amino alcohols and their N-protected derivatives (Cbz, t-Boc, and Fmoc) are versatile building blocks, auxiliaries, ligand or resolving agent in asymmetric synthesis for biological and pharmaceutical researches. applications are present in the field of antitumor, anesthetic, antipasmodic, hepatotoxic, antiinflammatory or anti-HIV activities.  Their derivatives include the forms of;

  • C-terminal peptibiols
  • Amphiphylic antibacterial peptides
  • Oligocarbamates
  • Analogs of peptides
  • Aziridines, Halogen aminoalkyls
  • Enantiomerical alpha-alkyl mono and diamines
  • Enantiomerical beta-substituted amines
  • Enantiomerical beta-amino acids beta-amino sulfoxides, beta-amino sulfides and
  • beta-amino thiols.
  • The precursors of diverse compounds such as statines, sphingolipides and peptide isosteres.
SALES SPECIFICATION

APPEARANCE

clear to yellow  liquid

ASSAY

99.0% min

Optical rotation

-29° ~ -32° (C=1 in toluene)

TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
REMARKS
Hazard Symbols: , Risk Phrases: 36/37/38, Safety Phrases: 26-36
PRICE

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