MUSK KETONE

PRODUCT IDENTIFICATION

CAS NO 81-14-1

MUSK KETONE

EINECS NO. 201-328-9
FORMULA C14H18N2O5
MOL WT. 294.31

H.S. CODE

2914.70.1000

UN NO.

3077

TOXICITY

Oral Rat LD50: > 10gm/kg
SYNONYMS Acetyl-dinitro-butyl-xylene;
1-[4-(1,1-Dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]ethanone; 4'-tert-Butyl-2',6'- dimethyl- 3',5'-dinitro- acetophenone; 4'-tert-Butyl-2',6'-dimethyl-3',5 '-dinitroacetophenone; Ketone moschus; 2,6-Dinitro-3,5-dimethyl-4-acetyl- tertbutylbenzene; 1-Acetyl-4-tert-butyl-2,6- dimethyl-3,5- dinitrobenzene; 1-[4-(1,1-Dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]ethanone; Dinitro-tert-butylxylyl methyl ketone; Ketone musk; 1-(4-tert-Butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanone;
SMILES c1(c(c(c(C(C)=O)c(c1[N+](=O)[O-])C)C)[N+](=O)[O-])C(C)(C)C

CLASSIFICATION

Antineoplastic agent, Ketone, Fragrance, Perfume ingredient, masking agent

EXTRA NOTES

Increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to yellowish crystals

MELTING POINT

135 - 139 C
BOILING POINT 395 C
SPECIFIC GRAVITY  

SOLUBILITY IN WATER

Insoluble
SOLVENT SOLUBILITY Soluble in alcohol, paraffin oil and phthalates
pH  
VAPOR DENSITY

 

AUTOIGNITION  

REFRACTIVE INDEX

 
NFPA RATINGS Health: 1; Flammability: 0; Reactivity: 0
FLASH POINT  
STABILITY Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS

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Local: Musk: any of various powerful-smelling substances obtained originally from the musk glands of male musk deer during the mating season for sexual attraction or from certain animals such as otter or civet. It is used in perfume as a scent and fixative. It is obviously the first importance in perfumery as it features the better properties in not only penetration but also persistency than any other known substance. It scents huge space without even small loss of weight. But synthetic musks should replace for natural must to protect animals. Muscone, 3-Methylcyclopentadecanone, is the major constituent of natural musk. The odoriferous nucleus of natural musk is the C-16 cyclic ketone (cyclopentadecanone). But synthetic musklile products are based on the symmetry of the three nitro groups or on polycyclic and cyclopentadecanone structure. The synthetic musklike products include:

SALES SPECIFICATION

APPEARANCE

white to yellowish crystals
CONTENT 98.0% min
TRANSPORTATION
PACKING  
HAZARD CLASS  
UN NO. 3077

OTHER INFORMATION

Hazard Symbols: XI, Risk Phrases: 38, Safety Phrases: 26-36
SYNTHETIC MUSK-LIKE COMPOUNDS
  • Nitro Class
    • Musk Xylol  (2,4,6-Trinitro-1,3-dimethyl-5-tert-butylbenzene, CAS RN: 81-15-2 )
    • Musk Ketone (4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone, CAS RN: 81-14-1 )
    • Musk Ambrette (4-tert-Butyl-2,6-dinitro-3-methoxytoluene, CAS RN: 83-66-9)
    • Musk Tibetene (5-tert-Butyl-1,2,3-trimethyl-4,6-dinitrobenzene, CAS RN: 145-39-1 )
    • Musk Moskene (2,3-Dihydro-1,1,3,3,5-pentamethyl-4,6-dinitro-1H-Indene, CAS RN: 116-66-5)
  • Polycyclic Musk Class
    • Musk GX (1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta-gamma-2-benzopryan, CAS RN: 1222-05-5 )
    • Tonalide (1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one, CAS RN: 1506-02-1)
    • Celestolide (4-Acetyl-6-t-butyl-1,1-dimethylindan, CAS RN: 13171-00-1)
    • Phantolide (5-Acetyl-1,1,2,3,3,6-hexamethyl indan, CAS RN: 15323-35-0)
    • Traseolide (5-Acetyl-3-isopropyl-1,1,2,6-tetramethylindane, CAS RN: 68140-48-7)
    • Versalide (1,1,4,4-Tetramethyl-6-ethyl-7-acetyl-1,2,3,4-tetrahydronaphthalene, CAS RN: 88-29-9)
    • 3,4,6,7,8,9-Hexahydro-4,6,6,9,9-pentamethyl-1H-naphtho[2,3-C]pyran (CAS RN: 1922-67-4)
    • 2,4-Dimethyl-2-(1,1,4,4-tetramethyltetralin-6-yl)-1,3-dioxolane (CAS RN: 131812-67-4)
  • Macrocyclic Class
    • Muscone (3-Methylcyclopentadecanone CAS RN: 541-91-3)
    • Exaltone (Cyclopentadecanone, CAS RN: 502-72-7)
    • Cervolide (1,6-Dioxacycloheptadecan-7-one, CAS RN: 6707-60-4)
    • Musk Ambrettolide ((Z)-Oxacycloheptadec-8-en-2-one, CS RN: 123-69-3)
    • Exaltolide (Oxacyclohexadecan-2-one, CAS RN: 106-02-5)
    • Musk T (1,4-Dioxacycloheptadecane-5,17-dione, CAS RN: 105-95-3)
    • Ambrettolide (Oxacycloheptadec-10-en-2-one, CAS RN: 28645-51-4)
    • Civetone ((Z)-9-Cycloheptadecen-1-one, CAS RN: 542-46-1)
    • Cyclopentadecanone (CAS RN: 502-72-7)
    • Ambretone (5-Cyclohexadecenone, CAS RN:37609-25-9)
    • Musk R1 (11-Oxahexadecanolide, CAS RN: 3391-83-1 )
    • 1,4-Dioxacyclohexadecane-5,16-dione (CAS RN: 54982-83-1)
PRICES

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