ISOAMYL SALICYLATE

PRODUCT IDENTIFICATION

CAS NO. 87-20-7

ISOAMYL SALICYLATE

EINECS NO. 201-730-4
FORMULA C5H11C(O)OC6H4OH
MOL WT. 208.26

H.S. CODE

2918.23
SMILES

 

TOXICITY

 
SYNONYMS Isoamyl ortho-hydroxybenzoate;
Salicylic acid, Isopentyl ester; Isoamyl o-hydroxybenzoate; Isopentyl salicylate; Isoamylester kyseliny salicylove; Isopentyl-2-hydroxyphenyl methanoate; 3-Methylbutyl 2-hydroxybenzoate; Orchidee; Sanfoin; o-Hydroxy Benzoic acid, 3-Methylbutyl ester;

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE clear liquid

MELTING POINT

-75 C
BOILING POINT 277 - 278 C
SPECIFIC GRAVITY 1.05 - 1.055

SOLUBILITY IN WATER

Insoluble
pH  
VAPOR DENSITY

 

AUTOIGNITION  

REFRACTIVE INDEX

1.507 - 1.509
NFPA RATINGS Health: 1; Flammability: 2; Reactivity: 0
FLASH POINT 26 C
STABILITY Stable under ordinary conditions

APPLICATIONS

The carboxyl group (–COOH) can react with alcohols, forming numerous esters. Many esters have distinctive odors, which are commonly used as fragrance or flavour agents. Salicylates has a pleasant odor resembling wintergreen. Salicylates also have analgesic, antipyretic, and antiinflammatory activity.

Isoamyl Salicylate is used in perfumery and fragrance. Odor description: herbal woody orchid floral.

SALES SPECIFICATION

APPEARANCE

clear liquid
ASSAY 98.0% min
ACID VALUE 2.0  max (mg KOH/g)
TRANSPORTATION
PACKING 170kgs in drum
HAZARD CLASS 3 (Packing Group: III)
UN NO. 1195
OTHER INFORMATION
FEMA NO. : 2084
GENERAL DESCRIPTION OF SALICYLIC ACID
Salicylic Acid is a white crystalline powder or needle-shaped crystals with sweetish taste; soluble in acetone, ether, alcohol, boiling water, benzene and turpentine, sparingly soluble in chloroformbenzene, slightly soluble in water; melts at 158°C. The sodium salt form (sodium salicylate) is common commercially, prepared from mainly sodium phenolate with carbon dioxide under heating and pressure. It contains both a hydroxyl and a carboxyl group, which react with either an acid or an alcohol. The carboxyl group forms esters with alcohols; e.g. methyl salicylate is formed with methanol, which used in food flavorings and preservatives; menthyl salicylate is formed with methanol, which is used in suntan lotions. The hydroxyl group reacts with acetic acid to form acetylsalicylic acid (called aspirin) which is the most widely common antiseptic and antipyretic agent. Phenyl salicylate (called salol) is formed with phenol, which is also used as an antiseptic and antipyretic agent. The sodium salt (Sodium salicylate), a shiny white powder, is used for antiseptics preparations and as a preservative. In addition to its analgesic and antipyretic properties, salicylic acid possesses keratinolytic properties and fungicidal properties. It ans its derivatives are used in the treatment of hyperkeratotic, dandruff, ichthyosis and psoriasis as well as in the treatment of fungal skin infections such as tinea. Para-Aminosalicylic acid (abbreviated PAS and PASA) is an analogue of para-aminobenzoic acid (abbreviated PABA) that inhibits folic acid synthesis in Mycobacterium tuberculosis and is bacteriostatic, inhibits growth and multiplication of the tubercle bacillus. Para-Aminosalicylic acid and its sodium salt (sodium p-Aminosalicylate) are bacteriostatic against mycobacteria and used in the treatment of tuberculosis; administered orally. Brand names are Tubasal, Nemasol Sodium and etc. Aminosalicylic acids are pharmaceutically active ingredients including anti-infectives against colds, flu, or other virus infections. Mesalamine (5-aminosalicylic acid, abbreviated 5-ASA) an active metabolite of sulfasalazine, used to treat inflammation of the rectum and lower colon, mild to moderate ulcerative colitis proctosigmoiditis, and proctitis. Para-Aminosalicylic acid (4-hydroxybenzoic acid) is used as an intermediate of bacteriostatic agent specially for parabens (alkyl esters of p-hydroxy benzoic acid) which used in food and personal care products as a preservative. It is applied in the production of liquid crystal polymers. It is also used as an intermediate of dyes, insecticides, pharmaceutical, pesticides and other chemical compounds. Salicylic Acid and its derivatives are important for the preparation of other pharmaceutical products, dyes, flavours, and preservatives.