alpha-TROPANOL
2,3-Dihydro-3alpha-hydroxytropidine; 3-alpha-Tropanol; 3alpha-Tropanol; Tropine; 3-Tropanol; 8-Methyl-8-azabicyclo(3.2.1)octanol; Tropanol; Tropin; endo-8-Methyl-8-azabicyclo(3.2.1) octan-3-ol; 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol; 3-endo-8-Methyl-8-azabicyclo(3.2.1)octanol; 8-Methyl-8-azabicyclo[3.2.1.]octan-3endo-ol;

 
 

PRODUCT IDENTIFICATION

CAS RN

 120-29-6; 28390-68-3, 180515-56-4 (hydrate)

EINECS RN

 204-384-2

FORMULA

 C8H15NO

MOLE WEIGHT

 141.21

CHEMICAL FAMLY

 Tropane

CATEGORY

tropane alkaloid

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

 white to slightly yellow crystalline powder

MELTING POINT

 62 - 64 C

BOILING POINT

 233 C

DENSITY

 1.04

SOLUBILITY IN WATER

 100 g/l ( freely soluble in alcohol soluble in ether and chloroform)

pH

 11 - 12.5 (10%  solution)

VAPOR DENSITY

 

REFRACTIVE INDEX

  

FLASH POINT

 

 
STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBILITIES

 Strong oxidizing agents
DECOMPOSITION
PRODUCTS

Carbon oxides, Nitrogen oxides
POLYMERIZATION Has not been reported

NFPA RATINGS

Health Hazard: 1, Fire: 0, Reactivity Hazard: 0

 

SAFETY NOTES

HAZARD OVERVIEW

 Harmful by inhalation and if swallowed.

EYE

 May cause eye irritation

SKIN

May cause skin irritation. May be harmful if absorbed through skin.

INGESTION

May be harmful if swallowed.

INHALATION

May be harmful if inhaled. May cause respiratory tract irritation.

CHRONIC

  

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

3335
HAZARD CLASS

9
PACKING GROUP

 

HAZARD SYMBOL

XN

RISK PHRASES

 20/22

SAFETY PHRASES

 

 

GENERAL DESCRIPTION & EXTERNAL LINKS
Tropine is the tropane core structure part (nitrogenous bicyclic nucleus) and tropic acid is the ester part of atropine (a tropane alkaloid). Atropine is hydrolysed to tropine and tropic acid. Tropine also called tropanol (chemical designation: 8-Methyl-8-azabicyclo(3.2.1)octan-3-ol) is an alcohol which forms esters. There are stereoisomers endo- and exo- stereoisomers.
alpha-Tropanol

CAS RN

 120-29-6
Trivial name Tropine
Systematic Name endo-8-Methyl-8-azabicyclo(3.2.1)octan-3-ol
Melting point 63 C
Boiling point 229 C

Natural esters

Hyoscyamine, Atropine
beta-Tropanol

CAS RN

 135-97-7
Trivial name Pseudotropine
Systematic Name exo-8-Methyl-8-azabicyclo(3.2.1)octan-3-ol
Melting point 108 -109 C
Boiling point 240 - 241 C

Natural esters

Cocaine, Troparil
 

Tropeine is an ester of tropine, either a natural alkaloid derived from plants or semi-synthetic. The best known members of tropeine natural alkaloids are Hyoscyamine, Atropine, Scopolamine, Ecgonine, Cocaine.

Tropinone, bicyclic aminoketone, is a useful synthetic precursor in the preparation of many tropane ring compounds including tropine and atropine.

nor- is a chemical acronym and prefix to describe the lacking of methyl chains that are part of a larger molecule. Nortropine is a tropine compound lacking methyl chain at nitrogen carbon.

 

SALES SPECIFICATION

APPEARANCE

 white to slightly yellow crystalline powder

ASSAY

99.0% min

WATER

2.0%

ASH

0.1% max

pH

 11 - 12.5 (10%  solution)

 

PACKING

 

 

PRICE INFORMATION