PALMATINE CHLORIDE

Synonyms. Palmatine chloride; Berbericinine chloride; 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo(a,g)quinolizinium chloride; 7,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxyberbinium chloride; O,O-Dimethyldemethyleneberberine chloride; Palmatin chloride;

PALMATINE CHLORIDE

 

PRODUCT IDENTIFICATION

CAS RN

3486-67-7 (base), 10605-02-4 (chloride)

EINECS RN

 

FORMULA

C21H22ClNO4

MOLE WEIGHT

387.86

H.S CODE

2939.99.0000

SMILES

[n+]12c(c3cc(OC)c(cc3CC2)OC)cc2c(c1)c(c(OC)cc2)OC.[ClH-]

CLASSIFICATION

Alkaloid, Quaternary ammonium compound, Isoquinolin,

EXTRA NOTES

A protoberberine alkaloid found in several plants including Phellodendron amurense, Rhizoma coptidis/Coptis Chinensis and Corydalis yanhusuo

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

yellow oily liquid

MELTING POINT

 

BOILING POINT

206 C

DENSITY

 

SOLUBILITY IN WATER

 

SOLVENT SOLUBILITY  

VAPOR DENSITY

 

AUTOIGNITION TEMP

 
pH

 

REFRACTIVE INDEX

 

FLASH POINT

112 C

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

DECOMPOSITION PRODUCTS

Carbon oxides, nitrogen oxides (NOx), Hydrogen chloride gas

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health hazard: 1 Fire: 1 Reactivity Hazard: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - Palmatine

PubChem Compound Summary - Palmatine chloride

Drug Bank -  Palmatine

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Palmatine

http://www.ebi.ac.uk/chebi/ -  Palmatine

http://www.ncbi.nlm.nih.gov/ -  Palmatine

http://www.sciencedirect.com/
Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivores

http://www.ncshm.re.kr/
Palmatine attenuates D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure in mice

Local

Palmatine Moles

CAS RN

Calystigine

131-04-4

(-)-Tetrahydropalmatine 483-14-7
Cryptopalmatine 2292-20-8
Tetrahydropalmaline chloride 2506-20-9
Palmatine 3486-67-7
Palmatine iodide 4880-79-9
Tetrahydropalmatine hydrochloride 4880-82-4
D-Tetrahydropalmatine hydrochloride 6024-83-5
DL-Tetrahydropalmatine hydrochloride 6024-85-7
Tetrahydropalmatine 10097-84-4
Palmatine chloride 10605-02-4
13-Methylpalmatine chloride 10605-03-5
L-8-Oxotetrahydropalmatine 77519-57-4
Benzyltetrahydropalmatine 114090-45-8
7-(Bromoethoxyphenyl)tetrahydropalmatine 121447-96-9
Palmatine chloride hydrate

171869-95-7

 

SALES SPECIFICATION

APPEARANCE

yellow powder

PURITY

97.0% min

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

2811

HAZARD SYMBOL

6.1
PACKING GROUP III

 

SAFETY INFORMATION

HAZARD OVERVIEW

OSHA Hazards:Target Organ Effect. Target Organs:Eyes, Kidney, Liver, Heart

GHS

 

SIGNAL WORD

Warning

PICTOGRAMS

HAZARD STATEMENTS

H302 H315 H319 H332

P STATEMENTS

P305+P351+P338

EC DIRECTIVES

 

HAZARD CODES

Xn Harmhul

RISK PHRASES

20/22-36/38

SAFETY PHRASES

24-45

 

PACKING

 

 

PRICE INFORMATION (171869-95-7 chloride hydrate)