Information Portal (U.S. National Library of Medicine) - gamma-Valerolactone
(Kyoto Encyclopedia of Genes and Genomes) - gamma-Valerolactone
Safety Data Sheet
Substances Data Bank - gamma-Valerolactone
Lactone is an internal cyclic monoester
(anhydride) derived from the hydroxyl and carboxyl radicals
of gamma or delta hydroxy acids by the removal of a
H2O between a carboxyl and a hydroxyl group in the same
molecule; gamma-hydroxybutyric acid forms gamma-butyrolactone
and delta-hydroxydecanoic acid forms delta-decalactone
spontaneously. In result, prefixes describe the ring
size: beta- is for 4-membered ring), gamma- , 5-membered,
and delta-, 6-membered ring. Lactone moiety is important
in the field of perfumery, vitamins, and and the antibiotics.
Lactone undergoes the reactions of hydrolysis, reduction,
aminolysis, michael reaction.