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| trans-1-CINNAMYL PIPERAZINE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 87179-40-6 |
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| EINECS NO. | ||
| FORMULA | C13H18N2 | |
| MOL WT. | 202.30 | |
| H.S. CODE | ||
| TOXICITY | ||
| SYNONYMS | trans-1-cinnamyl Hexahydropyrazine; | |
| RAW MATERIALS |
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | clear to light yellow semi-solid | |
| MELTING POINT | 39 - 40 C | |
| BOILING POINT | ||
| SPECIFIC GRAVITY |
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| SOLUBILITY IN WATER | ||
| AUTOIGNITION |
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| pH | ||
| VAPOR DENSITY | ||
| NFPA RATINGS | Health: ; Flammability: ; Reactivity: | |
| REFRACTIVE INDEX | 1.574 - 1.576 | |
| FLASH POINT |
> 110 C | |
| STABILITY | Stable under ordinary conditions | |
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GENERAL DESCRIPTION & APPLICATIONS |
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Piperazine is a heterocyclic compound containing four carbon atoms and two of
nitrogen at 1,4 position ( als called 1,4-hexahydropyrazine). It is a
deliquescent crystalline compound melting at 105 C; soluble in water, alcohol,
glycerol, and glycols. It is used as a main ingredient of anthelmintics used to
treat intestinal roundworms (ascariasis) infection in human and poultry and to
treat pinworms (enterobiasis; oxyuriasis) by altering cell membrane permeability
and causing hyperpolarization of the membrane. Piperazine is a main moiety in
psychoactive drugs. Piperazine class drugs are suspected of ecstasy substitutes.
Benzylpiperazine is bannaed in many countries. Nitrogen in piperazine ring plays
an important role in biological research and drug manufacturing industry
including the preparation of anthelmintic, antiallergenic, antibacterial,
antihistamic, antiemetic and antimigraine agents. The piperazine ring and
piperazine derivatives are important cyclic components in industrial field as
raw
materials for hardener of epoxy resins, corrosion inhibitors, insecticides,
accelerators for rubber, urethane catalysts and antioxidants.
Trans-1-cinnamyl-piperazine is known as the key intermediate for the synthesis of cinnarizine, an antihistamine for the prevention and treatment of motional illness. |
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| SALES SPECIFICATION | ||
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APPEARANCE |
clear to light yellow semi-solid | |
| CONTENT |
98.0% min | |
| TRANSPORTATION | ||
| PACKING | ||
| HAZARD CLASS | ||
| UN NO. | ||
| OTHER INFORMATION | ||
| Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 26-36 | ||
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