2',5'-DIMETHOXY-4'-CHLORO-ACETOACETANILIDE

PRODUCT IDENTIFICATION
CAS NO. 4433-79-8

2',5'-DIMETHOXY-4'-CHLORO-ACETOACETANILIDE

EINECS NO. 224-638-6
FORMULA C12H14ClNO4
MOL WT. 271.70
H.S. CODE  
TOXICITY  
SYNONYMS

C.I. 37613; AA254A;

Acetoacetic-2,5-Dimethoxy-4-Chloroaniline;   Naphthol AS-IRG; N-(4-chloro-2,5-dimethoxyphenyl)-3-oxo-Butanamide;
SMILES 
 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE

light brown powder

MELTING POINT 102 - 104 C
BOILING POINT  
SPECIFIC GRAVITY

 

SOLUBILITY IN WATER  
AUTOIGNITION  
pH  
VAPOR DENSITY  
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FLASH POINT

 

STABILITY Stable under ordinary conditions

APPLICATIONS
Acetoacetanilide is used in manufacturing agricultural chemicals, coating materials, dyes and pigments ( the dry colors generally referred to as Hansa and benzidine yellows) as well as a co-promoters for unsaturated polyesters. Diketene derivativesa (mainly cetoacetic acid derivatives and heterocycles) have versatile applications including making agrochemicals, dyes, pigments, pharmaceuticals including vitamins, and stabilizers for PVC and polyester. Acetoacetic acid and its esters contain active methylene groups which have relatively acidic alpha-protons due to H atoms adjacent to two carbonyl groups. The reactivity of its methylene group provide the sequence of reactions of alkylation, hydrolysis of the esters and decarboxylation resulting in substituted ketones.

Benzoic acid derivatives substituted by hydroxy group or ether containing oxygen atom have active bacteriostatic and  fragrant properties. They are typically used in pharmaceutical and perfumery industry. The destructive metabolic property of oxygen containing benzoic acid derivatives such as protocatechuic acid (3,4-dihydroxybenzoic acid) and veratric acid (3,4-dimethoxybenzoic acid) is used in the application for pharmaceuticals. Protocatechuic acid is a catabolite of epinephrine. Prazosin, a peripheral vasodilator and antihypertensive, is also an example of the application of veratric acid. Hydroxy and ether substituted benzoic acids feature analogue metabolite of aspirin (acetylsalicylic Acid). They are used as intermediates for pharmaceuticals (especially for antipyetic anlgesic, antirheumatism) and other organic synthesis. They are used as matrix for ionization of peptides, proteins and carbohydrates.

2',5'-Dimethoxy-4'-Chloro-Acetoacetanilide is used as an intermediate for dyes and pigments (especailly yellow colors).
SALES SPECIFICATION

APPEARANCE

light brown powder

PURITY

99.0% min

MELTING POINT 102 - 104 C
INSOLUBLES

0.05% max

TRANSPORTATION
PACKING 25kgs in bag
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OTHER INFORMATION