|
NARINGIN |
| Synonyms. Naringin; 5-Hydroxy-2-(4-hydroxyphenyl)-7-(2-O-alpha-L-rhamnopyranosyl-beta-D- glucopyranosyloxy)-4 -chromanon; Naringenin-7-beta-neohesperidoside; Naringoside; 7-(2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D- glucopyranosyloxy)-2,3-dihydro-4',5,7- trihydroxyflavone;Naringenin-7-beta-neohesperidoside; 4′,5,7-Trihydroxyflavanone 7-rhamnoglucoside; Naringenine-7-rhamnosidoglucoside; Other RN:10236-69-8, 109010-50-6, 11032-31-8, 17784-35-9, 30174-44-8, 30552-25-1, 38664-96-9 |
|
|
| PRODUCT IDENTIFICATION | |
|
CAS RN |
10236-47-2 |
|
EINECS RN |
233-566-4 |
|
FORMULA |
C27H32O14 |
|
MOLE WEIGHT |
580.23 |
|
H.S CODE |
2938.90.0000 |
|
SMILES |
c12c(C(C[C@@H](O1)c1ccc(O)cc1)=O)c(cc(c2)O[C@H] 1[C@H](O[C @H]2[C@@H]([C@@H]([C@@H](O)[C@@H] (O2)C)O)O)[C@H]([C@H](O) [C@H](O1)CO)O)O |
|
CLASSIFICATION |
Natural Dye |
|
EXTRA NOTES |
Biochem/physiol Actions:Naringin, a flavanoid in grapefruit and other citrus fruits, potently inhibits intestinal organic anion-transporting polypeptide 1A2 (OATP1A2). Grapefruit juice thereby reduces bioavailability of many pharmacological agents taken at the same time. sigmaaldrich |
|
|
| PHYSICAL AND CHEMICAL PROPERTIES | |
|
PHYSICAL STATE. |
White to yellowish powder |
MELTING POINT |
83 C |
|
BOILING POINT |
|
|
DENSITY |
|
|
SOLUBILITY IN WATER |
|
| SOLVENT SOLUBILITY | |
|
VAPOR DENSITY |
|
|
log P(octanol-water) |
-0.44 |
|
VAPOR PRESSURE |
|
|
AUTOIGNITION TEMP |
|
| pKa |
|
|
REFRACTIVE INDEX |
|
|
FLASH POINT |
|
|
| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions.Light sensitive |
|
INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
|
NFPA RATINGS |
Health:2, Flammability:0, Reactivity: 0 |
|
|
| EXTERNAL LINKS & GENERAL DESCRIPTION |
|
Wikipedia Linking - Naringin Google Scholar Search - Naringin Drug Information Portal (U.S. National Library of Medicine) - Naringin PubChem Compound Summary - Naringin Drug Bank - Naringin KEGG (Kyoto Encyclopedia of Genes and Genomes) - Naringin http://www.ebi.ac.uk/ - Naringin http://www.ncbi.nlm.nih.gov/ - Naringin
|
|
|
| SALES SPECIFICATION | |
|
APPEARANCE |
White to yellowish powder |
|
ASSAY |
98.0% min |
|
OPTICAL ROTATION |
-75° ~ -85° (c=1% ethanol) |
|
LOSS ON DRYING |
5.0% max |
|
HEAVY METALS |
10ppm max |
|
As |
1ppm max |
|
Pb |
3ppm max |
|
MICROBIOLOGICAL TEST |
Total Plate Count: 1000 organisms/g max |
|
PARTICLE SIZE |
100 mesh |
|
|
| TRANSPORT & REGULATORY INFORMATION |
|
|
UN NO. |
Not regulated |
| HAZARD CLASS |
|
| PACKING GROUP | |
|
|
| SAFETY INFORMATION |
|
|
HAZARD OVERVIEW |
May cause eye and skin irritation. May cause respiratory and digestive tract irritation. |
|
GHS |
|
|
SIGNAL WORD |
Warning |
|
PICTOGRAMS |
|
|
HAZARD STATEMENTS |
H315-H319-H335 |
|
P STATEMENTS |
P261-P305 + P351 + P338 |
| EC DIRECTIVES |
|
| HAZARD CODES |
|
|
RISK PHRASES |
36/37/38 |
|
SAFETY PHRASES |
22-24/25 |
|
|