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LAFUTIDINE |
| Synonyms. Lafutidine; (+-)-2-(Furfurylsulfinyl)-N-((Z)-4-((4-(piperidinomethyl)-2-pyridyl)oxy)-2-butenyl) acetamide; (+-)-2-(Furfurylsulfinyl)-N-(4-(4-(piperidinomethyl)-2-pyridyl)oxy-(Z)-2-butenyl)acetamide; N-(4-(4-Piperidinylmethyl)pyridyl-2-oxy)butenyl-2-(furfurylsulfinyl)acetamide; Protecadin; Stogar; Protecadin Other RN: 143375-16-0 |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
118288-08-7 |
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EINECS RN |
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FORMULA |
C22H29N3O4S |
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MOLE WEIGHT |
431.54 |
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H.S CODE |
2932.19.5000 |
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SMILES |
o1cccc1C[S@@](CC(NC\C=C/COc1nccc(c1)CN1CCCCC1)=O)=O |
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CLASSIFICATION |
Histamine H2 receptor antagonist, Gastrointestinal agent, Anti-ulcer agent. |
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EXTRA NOTES |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
off white to pale yellow crystalline powder |
MELTING POINT |
96 ~ 99 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
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| SOLVENT SOLUBILITY | |
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VAPOR DENSITY |
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log P(octanol-water) |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pH |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 2, Flammability:0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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Wikipedia Linking - Lafutidine Google Scholar Search - Lafutidine Drug Information Portal (U.S. National Library of Medicine) - Lafutidine PubChem Compound Summary - Lafutidine Drug Bank - Lafutidine KEGG (Kyoto Encyclopedia of Genes and Genomes) - Lafutidine http://www.ebi.ac.uk/ - Lafutidine http://www.ncbi.nlm.nih.gov/ - Lafutidine http://www.sciencedirect.com/Lafutidine, a novel histamine H2-receptor antagonist, increases serum calcitonin gene-related peptide in rats after water immersion-restraint stress http://www.ingentaconnect.com/ |
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| SALES SPECIFICATION | |
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APPEARANCE |
off white to pale yellow crystalline powder |
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ASSAY |
99.0% min |
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LOSS ON DRYING |
0.5% max |
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IMPURITY |
1.0% max (Total), 0.5% max (Individual) |
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Residue on ignition |
4.5 ~ 6.0 |
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MELTING POINT |
96 ~ 99 C |
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HEAVY METALS |
20ppm max |
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| TRANSPORT & REGULATORY INFORMATION |
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UN NO. |
Not regulated |
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| PACKING GROUP | |
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| PACKING |
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| PRICE INFORMATION |
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