PRODUCT IDENTIFICATION

108-46-3

H.S. CODE

TOXICITY

Oral rat LD50: 301 mg/kg

CLASSIFICATION

Dihydroxybenzene.

EXTRA NOTES

PHYSICAL AND CHEMICAL PROPERTIES

White to off-white needle crystals

3.8

AUTOIGNITION

608 C

NFPA RATINGS

REFRACTIVE INDEX

127 C

Stable under ordinary conditions.

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Resorcinol

Wikipedia Linking - Resorcinol

Google Scholar Search - Resorcinol

U.S. National Library of Medicine - Resorcinol

PubChem Compound Summary - Resorcinol

Drug Bank -  Resorcinol

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Resorcinol

ChEBI (http://www.ebi.ac.uk/chebi/) -  Resorcinol

NCBI (http://www.ncbi.nlm.nih.gov/) -  Resorcinol

Material Safety Data Sheet - Resorcinol

Hazardous Substances Data Bank - Resorcinol

EPA - Substance Registry Services - Resorcinol

Local:
GENERAL DESCRIPTION OF RESORCINOL: There are three isomeric compounds of dihydroxybenzene molecule structure, which all have traditional names respectively. The ortho (1,2) isomer is called catechol (Also known as catechin; pyrocatechol; pyrocatechuic acid), which forms clear crystals used as a photographic developer in solution and as a starting material to produce synthetic catecholamines which have important physiological effects as neurotransmitters and hormonesany (such as epinephrine,  adrenaline, norepinephrine, and dopamine). The meta (1,3) isomer is resorcinol (also known as resorcin), which forms clear needle crystals used in the production of diazo dyes and plasticizers. It is produced by sulfonating benzene with fuming sulfuric acid and fusing the resulting benzenedisulfonic acid with caustic soda. Resorcinol is used in resins as an UV absorber. It is used in manufacturing fluorescent and leather dyes and adhesives. Reaction with formaldehyde produces resins (resorcinol formaldehyde resins) used to make rayon and nylon. It is used as a pharmaceutical to treat acne and other greasy skin conditions in combination with other acne treatments such as sulfur. It is used as an anti-dandruff agent in shampoo and sunscreen cosmetics. It is also used as a chemical intermediate to synthesis pharmaceuticals and other organic compounds. The para (1,4) isomer is hydroquinone (also known as quinol), which forms clear prisms used as a photographic reducer and developer (except in color film). It is formed in large quantities by chemical reduction of benzoquinone. This compound is a general-purpose inhibitor, stabilizer, antioxidant, and intermediate. One of the major uses of hydroquinone is as an intermediate to make other inhibitors, stabilizers, antioxidants, agricultural chemicals, and dyes. Resorcinol and its derivatives are used in resins as UV absorbers. They are used in manufacturing fluorescent and leather dyes and adhesives (resorcinol formaldehyde resins). They are used as pharmaceuticals to treat acne and other greasy skin conditions in combination with other acne treatments such s sulfur. They are used as an anti-dandruff agent in shampoo and sunscreen cosmetics.

APPLICATIONS: Resorcinol is used in resins as an UV absorber. It is used in manufacturing fluorescent and leather dyes and adhesives (resorcinol formaldehyde resins). It is used as a pharmaceutical to treat acne and other greasy skin conditions in combination with other acne treatments such as sulfur. It is used as an anti-dandruff agent in shampoo and sunscreen cosmetics. It is also used as a chemical intermediate to synthesis pharmaceuticals and other organic compounds. Resorcinol is one of parent material of topical keratolytic agents.

KERATOLYTIC AGENTS

APPEARANCE

White to off-white needle crystals

CONTENT

106 C min

HAZARD OVERVIEW

GHS (Globally Harmonised System) Classification: Acute toxicity (Oral). Acute toxicity (Dermal). Skin irritation. Serious eye damage. Acute aquatic toxicity. Hazard statements: Harmful if swallowed. May be harmful in contact with skin. Causes skin irritation. Causes serious eye damage. Very toxic to aquatic life.

GHS

Danger

PICTOGRAMS

HAZARD STATEMENTS

H302-H313-H318-H400

P STATEMENTS

P273-P280-P305 + P351 + P338

RISK PHRASES

22-36/37/38

SAFETY PHRASES

22-26-36