|
|
|
| POTASSIUM CLAVULANATE | ||
|
PRODUCT IDENTIFICATION |
||
| CAS NO. | 58001-44-8
(Base) 61177-45-5 (Potassium) |
|
| EINECS NO. | 261-069-2, 262-640-9 | |
| FORMULA | C8H8NO5·K | |
| MOL WT. | 237.24 | |
|
H.S. CODE |
||
|
TOXICITY |
||
| SYNONYMS | Clavulanic Acid Potassium; | |
| Potassium [2R-(2a,3Z,5a)]-3-(2-hydroxyethylidene)-7 -oxo-4-oxa-1-azabicyclo [3.2.0] heptane-2-carboxylate; Clavulaninsäure Kalium; ácido clavulanico de potasio; Acide clavulanique potassium; | ||
|
CLASSIFICATION |
||
|
PHYSICAL AND CHEMICAL PROPERTIES |
||
| PHYSICAL STATE | white to off-white powder | |
| MELTING POINT | ||
| BOILING POINT | ||
| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER | ||
| pH | ||
| VAPOR DENSITY |
|
|
| AUTOIGNITION |
|
|
| NFPA RATINGS | ||
|
REFRACTIVE INDEX |
||
| FLASH POINT |
|
|
| STABILITY |
Stable under ordinary conditions |
|
|
GENERAL DESCRIPTION & APPLICATIONS |
||
| beta-Lactamase inhibitor to increase antibiotic effectiveness; used in combination with penicillins (mainly amoxicillin) to treat infections caused by beta-lactamase–producing organisms. Beta-lactamase enzymes are produced by some bacteria and have resistance ability to beta-lactam antibiotics. These enzymes deactivate the antibacterial properties of beta-lactam antibiotics by opening the beta-lactam ring. Beta-lactamase inhibitors have little antimicrobial functions themselves and are combined with an actual beta-lactam antibiotic. Beta-lactamase inhibitors' function is to bind beta-lactamase enzymes to form an inactive molecule so that the actual beta-lactam antibiotic access to the bacterial wall which it destroys. Beta-lactamase inhibitors include clavulanic acid, sulbactam, and tazobactam. | ||
| SALES SPECIFICATION (USP, BP) | ||
|
APPEARANCE |
white to off-white powder | |
|
BLEND |
Potassium clavulanate--silicon dioxide (1:1) | |
|
CONTENT |
38.5 - 44.5% (Clavulanic acid) |
|
|
WATER |
1.5% max |
|
| TRANSPORTATION | ||
| PACKING |
25kgs
in fiber drum
|
|
| HAZARD CLASS | ||
| UN NO. | ||
| OTHER INFORMATION | ||
| SHELF-LIFE:
3 years PRICE INFORMATION  |
||
|
|
|
|
|
