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| METOPROLOL TARTRATE | |||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 37350-58-6
(base) 56392-17-7 (tartrate) |
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| EINECS NO. |
253-483-7 (base) 260-148-9 (tartrate) |
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| FORMULA | (C15H25NO3)2·C4H6O6 | ||
| MOL WT. | 684.82 | ||
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H.S. CODE |
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TOXICITY |
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| SYNONYMS | Tartrato de metoprolol; | ||
| 1-(Isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanol (2:1) Dextro-tartrate salt; Lopresor; Metoprolol hemitartrate; Metoprolol tartrate (2:1); 1-(4-(2-methoxyethyl) phenoxy)-3-(1-methylethyl) amino) 2-Propanol, tartrate (2:1); Tartrate de metoprolol; | |||
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | White to off-white crystalline powder | ||
| MELTING POINT |
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| BOILING POINT | |||
| SPECIFIC GRAVITY | |||
| SOLUBILITY IN WATER | Soluble | ||
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SOLVENT SOLUBILITY |
soluble in CH2Cl2, CHCl3, and alcohol, insoluble in ether | ||
| pH | |||
| VAPOR DENSITY |
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| AUTOIGNITION |
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| NFPA RATINGS | |||
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REFRACTIVE INDEX |
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| FLASH POINT |
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| STABILITY |
Stable under ordinary conditions. |
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GENERAL DESCRIPTION & APPLICATIONS |
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| Metoprolol: a cardioselective beta1-adrenoreceptor blocking agent in the
treatment of hypertension, angina pectoris, and myocardial infarction.
Metoprolol tartrate, tartrate salt of metoprolol, is a white crystalline powder,
practically odorless; soluble in water; soluble in methylene chloride,
chloroform, and alcohol, insoluble in ether; chemically
(±)-1-(isopropylamino)-3-(p-(2-(methoxyethyl) phenoxy)-2-propanol (2:1)
dextro-tartrate salt; administered orally and intravenously. Examples of alpha-beta combined brokers
are carvedilol and labetalol, alpha-Brokers; alfuzosin, doxazosin, indoramin, phenoxybenzamine, phentolamine, prazosin,
tamsulosin, terazosin, thymoxamine and beta-blockers examples include atenolol, metoprolol, oxprenolol, propranolol (most of the generic names for
beta blockers end with 'olol'). |
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| SALES SPECIFICATION | |||
| BP/USP | |||
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APPEARANCE |
White to off-white crystalline powder | ||
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ASSAY |
99.0% min |
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| CLARITY OF SOLUTION |
Clear and transparent |
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LOSS ON DRYING |
0.3% max |
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RESIDUE ON IGNITION |
0.1% max |
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HEAVY METALS |
20ppm max |
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| TRANSPORTATION | |||
| PACKING |
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| HAZARD CLASS | |||
| UN NO. | |||
| OTHER INFORMATION | |||
| Shelf-life:
4 years PRICE INFORMATION  |
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| We respect the intellectual property of Yamanouchi's U.S.Patent Nos. 4,703,063, 4761,500, 4772,475 and 4,868,216, 4,987,152. We are not offering tamsulosin in the United States. | |||
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