LEVAMISOLE HYDROCHLORIDE

PRODUCT IDENTIFICATION
CAS NO. 14769-73-4 (Base)
16595-80-5 (Hydrochloride)

LEVAMISOLE
EINECS NO. 238-836-5, 240-654-6
FORMULA C11H12N2S·HCl
MOL WT. 240.75

H.S. CODE

  

TOXICITY
 
SYNONYMS (-)-Tetramisole hydrochloride;
L(-)-2,3,5,6-Tetrahydro-6-phenylimidazo(2,1-b)thiazole hydrochloride; (S)-(-)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride;

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to off-white crystalline powder
MELTING POINT 230 - 233 C
BOILING POINT  
SPECIFIC GRAVITY

 
SOLUBILITY IN WATER Soluble
pH

3.0 - 4.5 (5% aq. solution)
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

  

AUTOIGNITION

 
FLASH POINT

 
STABILITY Stable under ordinary conditions. Light sensitive.

APPLICATIONS
Levamisole, the active levo-form of tetramisole, is used as an anthelmintic in the treatment of many nematodes particularly in veterinary applications. It is also an immunomodulator as an adjunct with fluorouracil to make it work better against cancer of the colon following surgical resection of the primary tumor. Chemical designation is (L)-2,3,5, 6-tetrahydro-6-phenylimidazo [2,1-b] thiazole. The hydrochloride salt of levamisole is a white crystalline powder with odorless; soluble in water and methanol; slightly soluble in ethanol and methylene chloride; insoluble in ether; stable in acid aqueous media but hydrolyzes in alkaline (or neutral) solutions.

Anthelmintic (also spelled  anthelminthic) is a chemical substance used to expel or destroy tapeworms in domestic animals. Some common anthelmintic active ingredients classified by chemical structure include;

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SALES SPECIFICATION

APPEARANCE

 white to off-white crystalline powder

ASSAY

98.5 - 101.0%

OPTICAL ROTATION

-121±2° (C=0.9 in water

HEAVY METALS

20ppm max

SULFATED ASH

0.1% max

LOSS ON DRYING

0.5% max

CHLORIDE

0.1% max
TRANSPORTATION
PACKING
 
HAZARD CLASS 6.1 (Packing Group: III)
UN NO. 2811
OTHER INFORMATION
Hazard Symbols: T, Risk Phrases: 25, Safety Phrases: 36/37/39-45

PRICE INFORMATION