ISOTHIAZOLINONE CHLORIDE

PRODUCT IDENTIFICATION

CAS NO. 55965-84-9

Kathon 886

EINECS NO.  
FORMULA C4H5NOS.C4H4ClNOS
MOL WT. 115.16/149.59

H.S. CODE

2934.10.7000

TOXICITY

Oral Rat LD50: 53mg/kg
SYNONYMS Isothiazolinone chloride; Kathon 886; Kathon CG; CMIT/MIT mixture;
5-Chloro-2-methyl-3(2H)-isothiazolone mixt. with 2-methyl-3(2H)-isothiazolone; Chloromethylisothiazolione/Methylisothiazolinone (75%/25%); CMI/MI; MCI/MI; CIT/MIT; Microcare IT; Microcare ITL; Acticide 14; Acticide LGMicrocide III; ProClin 300; Slaoff 360; Somacide RS; Tret-O-Lite XC 215; Zonen F; Other RN: 229619-22-1, 70294-89-2, 72980-78-0, 96118-96-6
SMILES c1(Cl)cc(=O)n(s1)C.c1(n(scc1)C)=O

CLASSIFICATION

Disinfectant, Thiazoline, Fungicide, Bactericide, Preservative

EXTRA NOTES

EPA Pesticide Chemical Code 107103,107104 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

Clear light amber liquid

MELTING POINT

 

BOILING POINT

 

DENSITY 1.19
SOLUBILITY IN WATER Miscible
SOLVENT SOLUBILITY Miscible with lower alcohols, glycols, other hydrophilic organic solvents. Insoluble in petrolatum
pH 1.0 - 4.0
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

Health hazard: 3, Fire: 0, Reactivity Hazard: 0

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY

Stable under ordinary conditions. Light sensitive

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Google Scholar Search

http://apps.kemi.se/
Isothiazolines are used as preservatives in the paint industry, where they serve to protect the product from fungal and mould attacks. One of the more common products of this kind used to be Kathon®, a 1.5%-aqueous solution consisting of 1 part methylisothiazolinone (CAS No 2682-20-4), and 3 parts of chloromethylisothiazolinone (CAS No 26172-55-4). This mixture can also be identified with a specific CAS No, 55965-84-9. To avoid risk of allergy the much weaker 1,2-benzisothiazolinone (commonly called BIT) is used. This is above all used as a preservative in latex paints. These substances are used in paint, adhesives, jointing compounds, cutting fluids and detergents. Paint, adhesive and detergents are products sold for both professional and consumer use.

http://ec.europa.eu/
Kathonʂ 886 Biocide (current process) is defined as a combination of the two active ingredients produced by an integrated production process, resulting in an approximate total of 14% active ingredients, 16% magnesium nitrate, 10% magnesium chloride and 62% water.
The "mixture of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-Methylisothiazol-3(2H)-one with magnesium chloride and magnesium nitrate" is currently regulated as a preservative in the cosmetic directive (76/768/EEC) in annex VI, part 1, entry 39 with the maximum authorized concentration 0.0015% (15 ppm) of the mixture. The submission describes Kathonʂ CG as cosmetic grade at 1.5% active ingredient stabilized with magnesium nitrate. It is the formulated product sold to customers for cosmetic applications. Kathonʂ CG is a cosmetic preservative. The main uses are rinse-off products, such as shampoos, conditioners, gels and surfactants. The EU use concentration is a maximum of 15 ppm a.i. for rinse-off and leave-on products. However, the manufacturers recommend a maximum level of 7.5 ppm a.i. (0.05% by weight of product as supplied) for leave-on products. The manufacturers recommend CMI/MI as a preservative in shower gels, body washes, bubble baths, liquid soaps, shampoos, hair conditioners and wipes. The CMI/MI mixtures have wide applications in household (domestic) and industrial products.

Local:
Isothiazolinones  containing sulfur atom (S),  nitrogen (N), oxygen (O) at 3 position and  hydrogen (H) can find application for making broad-spectrum biocides and preservatives  such as  antiseptic agents,  bactericides, slimicides, and   fungicides.    The biggest application is in paint industry especially marine antifouling agent. They are also used in adhesives, cutting oils, water systems, cosmetics, household goods and wound protectant for pruning cuts. They are also used as pulp and wood impregnating agents as well as in leather, fur and polymer process. It is known to cause allergy and chemical burn if high concentration is used in personal care products and cosmetics.

The list of isothiazolinones include  

Material

CAS #

EINECS #
(4-Chlorobenzyl)-3(2H)-isothiazolone 26530-09-6

 

1,2-Benzisothiazolin-3-one 2634-33-5

220-120-9

2-Butyl-1,2-benzisothiazolin-3-one 4299-07-4

 

2-Methyl-4,5-trimethylene-4-isothiazolin-3-one 82633-79-2

 

2-Methyl-4-isothiazolin-3-one 2682-20-4

220-239-6

2-Methyl-3-isothiazolone hydrochloride

26172-54-3

247-499-3
2-Octyl-3(2H)-isothiazolone 26530-20-1

247-761-7

4,5-Dichloro-2-cyclohexyl-4-isothiazolin-3-one 57063-29-3

 

4,5-Dichloro-2-octyl-3(2H)-isothiazolone 64359-81-5

264-843-8

4-Chloro-2-octyl-3(2H)-isothiazolone 64359-80-4 264-842-2
5-Chloro-2-(4-chlorophenylmethyl)-3(2H)-isothiazolone 66159-95-3

 

5-Chloro-2-methyl-4-isothiazolin-3-one 26172-55-4

247-500-7

5-Chloro-2-methyl-3(2H)-isothiazolone, calcium chloride complex 57373-19-0

 

5-Chloro-2-methyl-2H-isothiazol-3-one hydrochloride

26530-03-0

247-760-1

2-Methyl-4-isothiazolin-3-one calcium chloride 57373-20-3

 

Mixtures of these materials

 

 

 
SALES SPECIFICATION

APPEARANCE

Clear light amber liquid

ASSAY

14.0 - 14.5%

CMIT

10.1 - 11.3%

MIT

3.0 - 4.2%

SPECIFIC GRAVITY

1.26 - 1.32

pH  VALUE

1.0 - 4.0

TRANSPORTATION
PACKING
25kgs in drum
HAZARD CLASS  
UN NO.  

PRICE INFORMATION