GAMMA-AMINOBUTYRIC ACID

PRODUCT IDENTIFICATION

CAS NO. 56-12-2

GAMMA-AMINOBUTYRIC ACID

EINECS NO. 200-258-6
FORMULA H2N(CH2)3COOH
MOL WT. 103.12

H.S. CODE

 

TOXICITY

 
SYNONYMS 4-Amino-n-butyric Acid; GABA; Piperidinic acid;
4-Aminobutyric acid; DL-4-Aminobutyric acid; Piperidinic acid;
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to off-white solid
MELTING POINT 195 C (Decomposes)
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 
FLASH POINT  
STABILITY

Stable under ordinary conditions

GENERAL DESCRIPTION & APPLICATIONS

Aminobutyric acid is a four-carbon carboxylic acid, to which an amino group is attached. There are three structural isomers, alpha, beta, gamma-. Alpha-aminobutyric acid is has an amino group substituted at the alpha, or 1 position on the carbon atom next to the acid group, while gamma-aminobutyric acid (GABA) at the terinal carbon (the gamma, or 4 position). Natural GABA exits in L-form only and can be found in plant and animal tissues. It is formed in the metabolism of L-glutamic acid.  It is the central nervous system postsynaptic inhibitory transmitter in the brain but is also found in several extraneural tissues, including kidney and pancreatic islet beta cells. Gamma- hydroxy butyric acid is an intermediate occurring in metabolism of GABA. There are several hydroxy butyric acid occur at elevated levels in some metabolic disorders.  In biological systems The GABA family products are the parent compounds for a number of psychoactive drugs covering sedation/hypnosis, anxiolysis, anticonvulsant activity, muscle relaxation and anterograde amnesia. Some examples are benzodiazepines, baclofen, bicuculline, barbiturates, picrotoxin, neurosteroids and the general anesthetics.
SALES SPECIFICATION

APPEARANCE

white to off-white solid
ASSAY

99.0% min

TRANSPORTATION
PACKING
 
HAZARD CLASS not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: n/a, Risk Phrases:n/a, Safety Phrases: 24/25