FLUVOXAMINE MALEATE

PRODUCT IDENTIFICATION

CAS NO. 54739-18-3 (Base)
61718-82-9 (Maleate)

FLUVOXAMINE

EINECS NO.  
FORMULA C15H21O2N2F3·C4H4O4
MOL WT. 434.41

H.S. CODE

 

TOXICITY

 
SYNONYMS LuVox; Faverin;
5-methoxy-4'-(trifluoromethyl) valerophenone-(E)-O-(2-aminoethyl)oxime maleate (1:1);
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to off-white crystalline powder
MELTING POINT 120 - 123 C
BOILING POINT

 

SPECIFIC GRAVITY

 

SOLUBILITY IN WATER sparingly soluble
pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

 

AUTOIGNITION

 

FLASH POINT

 

STABILITY Stable under normal conditions

GENERAL DESCRIPTION & APPLICATIONS

Fluvoxamine is a drug of Selective Serotonin Reuptake Inhibitor (SSRI) which interferes with serotonin ((chemically 5-hydroxytryptamine, 5-HT) transport, used to treat depression, anxiety, obsessive-compulsive disorders (OCD), eating disorders, and social phobias. Fluvoxamine is considered to cause less loss of sex-drive and other side effects than other SSRIs. Examples of SSRI include Fluoxetine (Prozac, Fontex), Paroxetine (Paxil, Seroxat), Sertraline (Zoloft), Escitalopram Oxalate (Lexapro), Citalopram (Celexa), Fluvoxamine Maleate (Luvox), Bupropion (Wellbutrin). SSRIs have been increasingly replacing cyclic antidepressants which have been the most common antidepressants due to less side effects and to minimize suicide attempt. Examples of tricyclic antidepressants include Amitriptyline (Elavil,Endep), Clomipramine (Anafranil), Desipramine (Norpramin, Pertofrane), Doxepin (Adapin, Sinequan), Imipramine (Tofranil), Nortryptyline (Pamelor), Protriptyline (Vivactil), Trimipramine (Surmontil)  and tetracyclic antidepressant is Maprotiline (Ludiomil).

SALES SPECIFICATION

BP/USP/CP

IDENTITY

pass

ASSAY

98.5 - 101.0%

LOSS ON DRYING

1.0% max

RESIDUE ON IGNITION

0.5% max

VOLATILE IMPURITY

pass

HEAVY METALS

20ppm max

TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 20/21/22, Safety Phrases: 36
PRICES

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