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| ETHYL AMINOBENZOATE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 94-09-7 |
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| EINECS NO. | 202-303-5 | |
| FORMULA | H2NC6H4CO2C2H5 | |
| MOL WT. | 165.19 | |
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H.S. CODE |
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TOXICITY |
Oral rat LD50: 3040 mg/kg | |
| SYNONYMS | Benzocaine; 4-Aminobenzoic acid ethyl ester; | |
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Ethyl 4-Aminobenzoate; Ethyl p-aminobenzoate; Ethylester kyseliny p-aminobenzoove; |
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | white to pale yellow crystalline powder | |
| MELTING POINT | 89 - 92 C | |
| BOILING POINT | 172 C | |
| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER | ||
| pH | ||
| VAPOR DENSITY |
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AUTOIGNITION |
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NFPA RATINGS |
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REFRACTIVE INDEX |
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| FLASH POINT | > 110 C | |
| STABILITY | Stable under ordinary conditions. | |
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APPLICATIONS |
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| Ethyl Aminobenzoate is used in as a local anaesthetic applied to medicines and cosmetics. It releases pain temporarily with the fuction of nerve numb. It is used as an intermedaite for the synthesis other chemical compounds. | ||
| SALES SPECIFICATION (BP/USP) | ||
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APPEARANCE |
White crystalline powder | |
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ASSAY |
99.5% min | |
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CLARITY IN EtOH |
Pass |
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| MELTING POINT | 89 - 92 C | |
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WATER |
0.2% max |
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RESIDUE ON IGNITION |
0.1% max |
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Fe |
40ppm max |
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SULFATE |
Pass |
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CHLORIN |
Pass |
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| TRANSPORTATION | ||
| PACKING | 25kgs in fiber drum | |
| HAZARD CLASS | ||
| UN NO. | ||
| OTHER INFORMATION | ||
| Hazard Symbols: n/a, Risk Phrases: n/a, Safety Phrases: 24/25 | ||
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GENERAL DESCRIPTION OF LOCAL ANESTHETC |
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| Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other sid. The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into para-aminobenzoic acid. Amide is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain), Chloroprocaine (Nesacaine), Cocaine, Tetracaine (Pontocaine), Benzocaine, Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest), Bupivacaine (Marcaine), Etidocaine (Duranest). | ||
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