DOXAZOSIN MESYLATE

PRODUCT IDENTIFICATION

CAS NO. 77883-43-3

DOXAZOSIN MESYLATE

EINECS NO.  
FORMULA C23H25N5O5·CH3SO3H
MOL WT. 547.58

H.S. CODE

2934.90

TOXICITY

 
SYNONYMS Doxazosin mesylate;
1-(p-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl) carbonyl)] piperazine monomethanesulfonate; 1-(4-amino-6,7-dimethoxy-2- quinazolinyl)-4-[ 4-(1,4-benzodioxan-2-yl) carpiperazin-1-yl)]-6,7-dimethoxyquinazoline mesylate

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE
white to off-white crystalline powder
MELTING POINT  
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER
Slightly soluble
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 
FLASH POINT

 

STABILITY Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS

doxazosin mesylate, a quinazoline derivative, is an alpha1-receptor antagonist used as an antihypertensive agent which blocks of alpha1-adrenergic receptors and has a longer half life than that of prazosin. The chemical designation 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-yl carbonyl) piperazine methanesulfonate. It is a white to off-white crystalline powder; slightly soluble in water, alcohols; soluble in dimethylsulfoxide, dimethylformamide ands acetic acid; insoluble in acetone and methylene chloride.
SALES SPECIFICATION

APPEARANCE

white to off-white crystalline powder

ASSAY

99.0% min (HPLC)

WATER

0.2% max

LOSS ON DRYING

0.5% max

TOTAL IMPURITY

1.0% max

HEAVY METALS

10ppm max

TRANSPORTATION
PACKING

 

HAZARD CLASS  
UN NO.  

PRICE INFORMATION

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