CHLOROPROCAINE HYDROCHLORIDE

PRODUCT IDENTIFICATION

CAS NO. 3858-89-7

CHLOROPROCAINE HYDROCHLORIDE

EINECS NO.  
FORMULA C13H19ClN2O2HCl
MOL WT. 307.22

H.S. CODE

 
SMILES

 

TOXICITY

 
SYNONYMS Nesacaine hydrochloride;
4-Amino-2-chloro-Benzoic acid, 2-(diethylamino)ethyl ester, hydrochloride; 2-(Diethylamino)ethyl 4-amino-2-chlorobenzoate hydrochloride; 2-Chloroprocaine hydrochloride;

CLASSIFICATION

 

GENERAL DESCRIPTION OF LOCAL ANESTHETIC

Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other sid. The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into para-aminobenzoic acid. Amide  is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain), Chloroprocaine (Nesacaine), Cocaine, Tetracaine (Pontocaine), Benzocaine, Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest), Bupivacaine (Marcaine), Etidocaine (Duranest).

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE White crystalline powder, odourless
MELTING POINT

176 C

BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER

Slightly soluble

pH 5 - 6.5
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS  

REFRACTIVE INDEX

 
FLASH POINT

 

STABILITY

Stable under ordinary conditions.

APPLICATIONS

Chloroprocaine, in the form of a hydrochloride, is a local anaesthetic.
SALES SPECIFICATION
BP93/USP23

APPEARANCE

White crystalline powder

ASSAY

98.5% min

SULFATE

0.2% max

TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XN, Risk Phrases: 26/27/28, Safety Phrases: 22-36/37/39-45