CETYLPYRIDINIUM CHLORIDE

PRODUCT IDENTIFICATION

CAS NO. 123-03-5; 136499-13-3; 27841-61-8 (Anhydrous)
6004-24-6 (Monohydrate)

CETYLPYRIDINIUM CHLORIDE 

EINECS NO. 204-593-9
FORMULA C21H38NCl·H2O
MOL WT. 358.07

H.S. CODE

2933.39

TOXICITY

Oral rat LD50: 200 mg/Kg
SYNONYMS Pyrisept; Ceepryn; Cetamium; Dobendan; Medilave;
Cepacol; hexadecylpyridinium chloride; 1-Hexadecylpyridinium chloride; Merocet; Pristacin; C16-alkylpyridinium chloride;
SMILES

 

CLASSIFICATION

DISINFECTANTS /

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE White powder
MELTING POINT 80 - 83 C
BOILING POINT

 

SPECIFIC GRAVITY

 

SOLUBILITY IN WATER Freely soluble (Insoluble in acetone, acetic acid, ethanol)
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 

FLASH POINT Not considered to be a fire hazard
STABILITY

Stable under ordinary conditions

APPLICATIONS

Cetylpyridinium Chloride is an antiseptic agent used alone or in combination with other drugs for oral and throat care. Active ingredients in mouthwash or dental caries prophylactic include;

Ingredient

CAS RN

Amosan 8059-88-9
Benzalkonium chloride 8001-54-5
Cetylpyridinium chloride 123-03-5
Chlorhexidine gluconate 18472-51-0
Chlorhexidine55-56-1
Dectaflur 36505-83-6
Eucalyptol 470-82-6
Hetaflur 3151-59-5
Hydrogen peroxide 7722-84-1
Ipexidine mesylate 69017-90-9
Listerine 51273-66-6
Meridol 120812-75-1
Metesculetol 52814-39-8
Methyl salicylate 119-36-8
Olaflur 6818-37-7
Rhatany 84775-95-1
Salifluor 78417-90-0
Sanguinarine 2447-54-3
Sodium monofluorophosphate 10163-15-2
Sodium fluoride 7681-49-4
Stannous fluoride 7783-47-3
Thymol 89-83-8
Tiodonium chloride 38070-41-6
Zinc chloride 7646-85-7
Zinc fluoride 7783-49-5
SALES SPECIFICATION

APPEARANCE

White powder

ASSAY

99.0 - 102.0%

WATER

4.5 - 5.5%

HEAVY METALS

20ppm max

MELTING POINT

79 C min

TRANSPORTATION
PACKING
25kgs in bag
HAZARD CLASS Not regulated
UN NO.  
GENERAL DESCRIPTION OF ANTISEPTIC AGENT

Antiseptic agent is a substance which kills or inhibits the growth of disease-causing bacteria and other microorganisms. It is essentially nontoxic to to be applied to the skin or mucous membranes. (Disinfectant including cresol, bleaching powder, and phenol is in general toxic to cells of the body). Common antiseptic agents are Benzalkonium Chloride, Cetrimide, Chlorhexidine, Hexachlorophene, Iodine Compounds, Mercury Compounds (Thimerosol), Alcohol and Hydrogen Peroxide, Hexamine Hippurate, Triclosan, Cetylpyridinium Chloride, And Dequalinium. Other substances which can be used for antiseptic purpose include Boric acid and volatile oils such as Methyl Salicylate.
Hexachlorophene and Benzalkonium Chloride are used primarily in hand or face washes. Benzalkonium Chloride must not be applied to areas which have not been fully rinsed as it is inactivated by organic compounds. Benzalkonium application many include disinfecting instruments and preservativing drugs in low concentration form.
Iodine compounds have the widest spectrum of antiinfectives against bacteria, fungi, spores, protozoa, viruses, and yeasts. Aqueous iodine are less effective than alcoholic solutions, but alcoholic component is drying and irritating to abraided skin. Povidone iodine is convenient to use as it is less irritating, but not as effective.
Chlorhexidine is used as a safe antiseptic or disinfectant to apply to prevent body infection and in oral rinses for treating sore gums and mouth ulcers and preventing plaque on teeth. It is used in the form of acetate, gluconate or hydrochloride, either alone or in combination with others such as cetrimide.
Cetrimide is an antiseptic agent with detergent properties. It has the wide spectrum of antiinfectives against bacteria and fungi. It is used as an ingredient of shampoos for treating seborrhoea and psoriasis. A very dilute solution can be applied topically for the relief of sore gums.
Hippuric Acid, an amino acid glycine, is excreted from the body and is used in urinary system drugs. Hexamine hippurates is helpful for preventing and treating infections of the urinary system; it acts by being transformed to formaldehyde.
Triclosan is a very popular antibacterial agent. It is used in hospitals for cleansing and disinfecting the skin of patients and surgeons. It is used in cosmetics, household goods and personal care products. It is also used in plastics and textiles for antibacterial activity purpose.
Cetylpyridinium chloride is used in oral rinses for cleaning mouth and treating minor throat or mouth infections and teething problems.
Dequalinium chloride is antiinfectives against bacteria and fungi. It is used in treating bacterial or fungal infections of mouth and throat.

 

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