APIGENIN

PRODUCT IDENTIFICATION
CAS NO. 520-36-5

APIGENIN

EINECS NO.

208-292-3

FORMULA C15H10O5
MOL WT. 270.24

H.S. CODE

  

TOXICITY

  
SYNONYMS Naringenin chalcone; 5,7,4'-Trihydroxyflavone;
4',5,7-Trihydroxyflavone; 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone; 5,7-Dihidroxi-2-(4-hidroxifenil)-4-benzopirona; 5,7-Dihydroxy-2-(4-hydroxyphényl)-4-benzopyrone;
PRICE

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CLASSIFICATION

NATURAL COLORANT / ANTIOXIDANT / FLAVONES /

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE yellow crystalline powder
MELTING POINT

315 C

BOILING POINT

 

SPECIFIC GRAVITY

 

SOLUBILITY IN WATER

Insoluble (soluble in DMSO, slightly soluble in hot ethanol)

pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

  

AUTOIGNITION

 

FLASH POINT

 

STABILITY Stable under normal conditions

GENERAL DESCRIPTION & APPLICATIONS
Apigenin is a bioflavone, considered to have a bioactive effect on human health as antioxidant, radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, immunity system modulater.
SALES SPECIFICATION

APPEARANCE

 yellow crystalline powder, odorless

ASSAY

80.0% min ( 98.0% 95.0%, 90.0% min)

RESIDUE ON IGNITION

2.0% max

LOSS ON DRY

5.0% max

HEAVY METALS

10ppm max

LEAD

10ppm max

ARSENIC

2ppm max

SOLVENTS RESIDUE

1000ppm max (ethanol)

PESTICIDES RESIDUE

100ppb max

MICROBIOLOGICALS

Total Aerobic: 1000 CFU/g max
E. Coli: negative
Salmonella: Negative
Mold and Yeast: 100 CFU/g
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: , Risk Phrases: 36/37/38, Safety Phrases: 26-36

GENERAL DESCRIPTION OF FLAVONOID
Flavonoid is any member of a class of widely distributed biological natural products containing aromatic heterocyclic skeleton of flavan (2-Phenylbenzopyran) but no nitrogen in plants. Generally, flavonoids are biological pigments providing colours from red to blue in flowers, fruit and leaves. Besides their coloring in plants, flavonoids have important roles in the growth and development of plants; protection against UV-B radiation; forming antifungal barriers; antimicrobial, insecticidal and oestrogenic activities; plant reproduction. Flavonoids also exhibit a wide range of biological properties including anti-microbial, insecticidal and oestrogenic activities. Flavonoids are usually classified into main 6 subgroups as below plus flavans, neoflavonoids, flavonols, aurons, catechins according to the structural patterns.
  • Flavonols (Hydroxy derivatives of flavone): Fisetin, Galangin, Kaempferide, Kaempferol, Morin, Myricetin, Myricitrin, Quercetin, Quercetrin, Rhamnetin, Robinin, Rutin, Spirenoside
  • Flavones (skeleton: 2-phenylchromen-4-one): Apigenin, Baicalein, Chrysin, Diosmetin, Diosmin, Flavone, Luteolin, Rpoifolin,Tangeretin, Techtochrysin, Rhamnazin, Nobiletin, Natsudaidain.
  • Isoflavones (skeleton: 3-phenylchromen-4-one): Daidzin, Genistein, Irilone, Luteone, Prunetin, Pratensein,
  • Flavonones (derivation by reduction of the 2(3) C=C bond): Eriodictyol, Hesperidin, Hesperetin, Likvirtin, Naringin; Naringenin; Pinocembrin
  • Flavanols (derivation by reduction of the keto group):(+)-Catechin, (+)-Gallocatechin, (-)-Epicatechin (EC), (-)-Epigallocatechin (EGC), (-)-Epicatechin 3-gallate (ECG), (-)-Epigallocatechin 3-gallate (EGCG), Theaflavin, Theaflavin 3-gallate, Theaflavin 3'-gallate, Theaflavin 3,3' digallate, Thearubigins
  • Anthocyanidins (aglycones of the glycoside anthocyanins): Apigeninidin, Cyanidin, Delphinidin, Diosmetinidin, Guibourtinidin, Fisetinidin, Luteolinidin, Malvidin, Pelargonidin, Peonidin, Robinetinidin, Tricetinidin, Capensinidin, Petunidin, Europinidin, Aurentinidin, Columnidin, 5-Desoxy-malvidin, 5-Desoxy-peonidin, Hirsutinidin, Rosinidin

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