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| AMRINONE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 60719-84-8 |
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| EINECS NO. | 262-390-0 | |
| FORMULA | C10H9N3O | |
| MOL WT. | 187.21 | |
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H.S. CODE |
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TOXICITY |
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| SMILES | ||
| SYNONYMS | 5-Amino-(3,4'-bipyridin)-6(1H)-one; | |
| 3-Amino-5-(4-pyridinyl)-2(1H)-pyridinone; | ||
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | yellow crystalline powder | |
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| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER | ||
| pH | ||
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AUTOIGNITION |
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NFPA RATINGS |
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REFRACTIVE INDEX |
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| FLASH POINT |
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| STABILITY | Stable under ordinary conditions. | |
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APPLICATIONS |
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| Amrinone, non-glycoside cardiotonic agent, is used in the short-term management of congestive heart failure unresponsive to digitalis, diuretics, or vasodilators. It is a phosphodiesterase inhibitor which prevents enzymatic breakdown of cyclic AMP with positive inotropic and vasodilator effects. Its chemical name is 5-Amino-(3,4'-bipyridin)-6(1H)-one. The lactate salt of amrinone is administered intravenously. | ||
| SALES SPECIFICATION (USP24) | ||
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APPEARANCE |
yellow crystalline powder | |
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ASSAY |
98.0% - 102.0% | |
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WATER |
1.0% max |
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INDIVIDUAL IMPURITY |
0.2% max (TOTAL 1.0% max) |
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SOLVENT RESIDUE |
0.1% max ( DMF, EtOH, Ethyl Ether) |
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| HEAVY METALS |
20ppm max |
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| TRANSPORTATION | ||
| PACKING |
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| HAZARD CLASS | ||
| UN NO. | ||
| OTHER INFORMATION | ||
| Hazard Symbols: T, Risk Phrases: 25, Safety Phrases: 28-45 | ||
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