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| AMBROXOL HYDROCHLORIDE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 23828-92-4 |
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| EINECS NO. | 248-111-5 | |
| FORMULA | C13H18Br2N2O·HCl | |
| MOL WT. | 414.57 | |
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H.S. CODE |
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TOXICITY |
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| SYNONYMS | trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol; | |
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE |
yellow to yellowish crystalline powder |
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| MELTING POINT | 235 - 240 C | |
| BOILING POINT | ||
| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER | ||
| pH | ||
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| AUTOIGNITION |
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REFRACTIVE INDEX |
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| FLASH POINT | ||
| STABILITY |
Stable under ordinary conditions. |
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GENERAL DESCRIPTION & APPLICATIONS |
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| Ambroxol is a metabolite of bromhexine. It is an expectoration improver and mucolytic agent used in the treatment of acute and chronic disorders characterized by the production of excess or thick mucus. It works to decrease mucus viscosity by altering its structure. It is chemically described as trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol. It is a white to yellowish crystalline powder; slightly soluble in water, ethanol; soluble in dimethylformamide, methanol; insoluble in chloroform and benzene; melting point 240 C; administered orally. | ||
| SALES SPECIFICATION | ||
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APPEARANCE |
white to yellowish crystalline powder | |
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IDENTIFICATION |
Complies Test A,B |
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| PURITY |
98.0 - 102.0% |
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| SULFATED ASH |
0.1% max |
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HEAVY METALS |
20ppm max |
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LOSS ON DRYING |
0.5% max |
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INDIVIDUAL IMPURITY |
0.1% max (Total impurity: 0.5% max) | |
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| OTHER INFORMATION | ||
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