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| ACITRETIN | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 55079-83-9 |
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| EINECS NO. | 2594744 | |
| FORMULA | C21H26O3 | |
| MOL WT. | 326.43 | |
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H.S. CODE |
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TOXICITY |
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| SYNONYMS | all-trans-Etretin; | |
| all-trans-9-(4-Methoxy- 2,3,6- trimethylphenyl)- 3,7-dimethyl-2,4,6,8- nonatetraenoic acid; | ||
| DERIVATION |
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE |
yellow to greenish crystalline powder |
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| MELTING POINT | ||
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| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER | ||
| pH | ||
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| AUTOIGNITION |
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| NFPA RATINGS | ||
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REFRACTIVE INDEX |
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| FLASH POINT | ||
| STABILITY |
Stable under ordinary conditions. |
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GENERAL DESCRIPTION & APPLICATIONS |
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| Acitretin, a retinoid, is used as an antipsoriatic in the treatment of severe psoriasis and various other skin disorders; administered orally. Chemical designation is all-trans-9-(4-methoxy- 2,3,6- trimethylphenyl)- 3,7-dimethyl-2,4,6,8- nonatetraenoic acid. It is a yellow to greenish-yellow powder. | ||
| SALES SPECIFICATION | ||
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APPEARANCE |
yellow to greenish crystalline powder |
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IDENTIFICATION |
Complies Test A,B |
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| PURITY |
98.0 - 102.0% |
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| SULFATED ASH |
0.1% max |
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HEAVY METALS |
20ppm max |
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LOSS ON DRYING |
0.5% max |
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INDIVIDUAL IMPURITY |
0.3% max (Total impurity: 1.0% max) | |
| TRANSPORTATION | ||
| PACKING |
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| HAZARD CLASS | 9 (Packing Group: III) | |
| UN NO. | 3077 | |
| OTHER INFORMATION | ||
| Hazard Symbols: T N, Risk Phrases: 61-36/38-50/53, Safety Phrases: 53-37/39-45-60-61 | ||
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