3-BENZOYLPYRIDINE

PRODUCT IDENTIFICATION
CAS NO. 5424-19-1

3-BENZOYLPYRIDINE

EINECS NO. 226-561-3
FORMULA C12H9NO
MOL WT. 183.21

H.S. CODE

  

TOXICITY

  
SYNONYMS phenyl-3-pyridinyl-Methanone
Phenyl-beta-pyridyl ketone Phenyl-3-pyridylketon (German) Fenil-3-piridilcetona (Spanish)   Phé nyl-3-pyridylcé tone (French) Phenyl 3-pyridyl ketone
SMILES

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE White to pale yellowish crystals
MELTING POINT 36 - 40 C
BOILING POINT

317 C

SPECIFIC GRAVITY

 

SOLUBILITY IN WATER Insoluble
pH  
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

 Health:1 Flammability: 1 Reactivity:0

AUTOIGNITION

 

FLASH POINT

150 C

STABILITY Stable under normal conditions

GENERAL DESCRIPTION & APPLICATIONS
PYRIDINE, also called azabenzene and azine, is a heterocyclic aromatic tertiary amine characterized by a six-membered ring structure composed of five carbon atoms and a nitrogen which replace one carbon-hydrogen unit in the benzene ring (C5H5N). The simplest member of the pyridine family is pyridine itself. It is colorless, flammable, toxic liquid with a unpleasant odor, miscible with water and with most organic solvents, boils at 115 C. Its aqueous solution is slightly alkaline. Its conjugate acid is called pyridinium cation, C5H5NH+, used as a oxidation agent for organic synthesis.. Pyridine is a base with chemical properties similar to tertiary amines. Nitrogen in the ring system has an equatorial lone pair of electrons, that does not participate in the aromatic pi-bond. Its aqueous solution is slightly alkaline. It is incompatible and reactive with strong oxidizers and strong acids, and reacts violently with chlorosulfonic acid, maleic anhydride, oleum, perchromates, b-propiolactone, formamide, chromium trioxide, and sulfuric acid. Liquid pyridine easily evaporates into the air. If it is released to the air, it may take several months to years until it breaks down into other compounds. Usually, pyridine is derived from coal tar or synthesized from other chemicals, mainly acetaldehyde and ammonia. Pyridine compounds are found in nature. For example, nicotine from tobacco, ricinine from castor bean, pyridoxine or vitamin B and P  products, alkaloids (such as coniine, piperine and nicotine), and etc. Some pyridine compounds consumed largely are

Picoline : Three structural isomers of methyl pyridines (alpha, beta, gamma- positions)
Lutidine : Six structural isomers of dimethyl pyridines (2,3-, ,24-, 2,5-, 2,6-, 3,4-, 3,5- positions)
Collidine : Three structural isomers of trimethyl pyridines (2,3,5-, 2,3,6-, 2,4,6- positions)
Pyrimidine: Pyridine alteration containing nitrogen atoms at positions 1 and 3
Piperidine: Hexahydropyridine (saturated form)
Nicotinic acid: pyridine-3-carboxylic acid

Pyridine and its derivatives are very important in industrial field as well as in bio chemistry. Nucleotide consist of either a nitrogenous heterocyclic base (purine or pyrimidine). Three major pyrimidines in living systems are cytosine, thymine, and uracil. Pyrimidine and its derivatives are biologically important components of nucleic acids (DNA, RNA) and coenzymes. Some pyridine system is active in the metabolism in the body. Certain nitrogenous plant products also have pyridine class compounds. They can be the parent compound of many drugs, including the barbiturates. Pyridine and its derivatives are used as solvents and starting material for the synthesis of target compounds such as insecticides, herbicides, medicines, vitamins, food flavorings, feed additives, dyes, rubber chemicals, explosives, disinfectants, and adhesives. Pyridine is also used as a denaturant for antifreeze mixtures, as a dyeing assistant in textiles and in fungicides. 3-Benzoylpyridine is used as an intermediate for pharmaceuticals and other organic synthesis.
SALES SPECIFICATION

APPEARANCE

 White to pale yellowish crystals

ASSAY

98.0% min

MELTING POINT

 36 - 40 C
WATER (K.F)

0.2% max

IMPURITY

3-Benzylpyridine : 1.0% max
4-Benzoylpyridine: 0.5% max
4-Benzoylpyridine : 0.5% max
TRANSPORTATION
PACKING
25kgs in   cardboard drum
HAZARD CLASS not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: n/a, Risk Phrases:n/a, Safety Phrases: 24/25-28A-37-45

GENERAL DESCRIPTION OF KETONE
Ketone is a class of chemical compounds contain the carbonyl group in which the carbon atom is covalently bonded to an oxygen atom. It has the general formula RCOR' where the groups R and R' may be the same or different, or incorporated into a ring (R and R' are alkyl, aryl, or heterocyclic radicals). The simplest example, R and R´ are methyl group, is acetone (also called 2-propanone, CH3COCH3) which is one of the most important ketones used in industry (low molecular weight ketones are general purpose solvents.) In the IUPAC system, the suffix -one is used to describe ketone with the numbering of the carbon atom at the end that gives the lower number. For example, CH3CH2COCH2CH2CH3 is named 3-hexanone because the whole chain contains six carbon atoms and the oxygen is connected to the third carbon from the lower number. Ketones can be made by the oxidation of secondary alcohols and the destructive distillation of certain salts of organic acids. Carbonyl group structures are: 

CARBONYL GROUP