2-OXINDOLE

PRODUCT IDENTIFICATION
CAS NO. 59-48-3

OXYINDOLE

EINECS NO. 200-429-5
FORMULA C8H7NO
MOL WT. 133.15

H.S. CODE

 2933.99

TOXICITY

  
SYNONYMS Oxindole; 1,3-Dihydroindol-2-one; 2-Oxindoline; 2-Oxoindoline;
1,3-Dihydro-2H-indol-2-one; Indol-2(3H)-one; 1,3-Dihydroindol-2-one; 1H-indol-2-ol; Oxindol;
SMILES

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE off-white crystalline powder
MELTING POINT 125 - 127 C
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER 9130 mg/l
pH  
VAPOR DENSITY

 

AUTOIGNITION  

REFRACTIVE INDEX

 

NFPA RATINGS Health: 1; Flammability: 0; Reactivity: 0
FLASH POINT

 

STABILITY Stable under normal conditions. Light sensitive

GENERAL DESCRIPTION & APPLICATIONS
Oxindole is the oxidized indole at 2 position. Isatin is the di-oxidized derivative of indol at 2 and 3 positions. The oxidized indole at 3 position is indoxyl which are oxidized further to indigo dye in air. Indican is a glucoside of indoxyl; found in the indigo plant. In biochemistry indican refers to the indoxylsulfate found in urine by bacteria action on tryptophan. Traditionally indole derivatives are important raw materials for dyestuffs. They are lactam structure compounds which are important in antibiotics. There cyclic ester structures are present in many alkaloids,auxins and flavorings (jasmine). They also show not only psychotropic activity but anticonvulsive activity. Some indolyl and indoxyl derivatives which produce insoluble indigo precipitates are used as chromogenic enzyme substrates for clinical diagnostics application environmental testing. They are used as biological dyes to stain certain cell components for cell analysis.

Molecular compounds of Oxindole

Product

CAS RN
2-Oxindole 59-48-3
1-Methyl-2-oxindole 61-70-1
1-Ethyl-2-indolinone 61-28-9
3-Hydroxy-2-oxoindole 61-71-2
Oxyphenisatin Acetate 115-33-3
Oxyphenisatine 125-13-3
Violacein 548-54-9
Isatin-3-oxime 607-28-3
3-Methyloxindole 1504-06-9
3-Hydroxy-3-phenyl-2-indolinone 1848-24-4
3-Methyleneoxindole 1861-29-6
3-(Methylimino)-2-indolinone 2058-70-0
2-Oxindole-3-acetic acid 2971-31-5
3-Hydroxy-3-methyloxindole 3040-34-4

Phenyloxindole

3335-98-6
3-(2-Aminoethyl)-2-indolinone hydrochloride 4993-84-4
Yohimbine oxindole 5074-58-8
Indole-2,3-diol 5638-85-7

5-Fluorooxindole

5641-41-4
5-Hydroxy-3-methyl-2-indolinone 6062-25-5
3-Hydroxy-3-(2-pyridylmethyl)-2-indolinone 6299-00-9
3-Acetonylidene-2-oxindole 6524-20-5

Methyl 2-oxindole-6-carboxylate

14192-26-8
Iminophthalimidine 14352-51-3
1-(2,6-Dichlorophenyl)indolin-2-one 15362-40-0
beta-3-Oxindolylalanine 16008-59-6

5-Chlorooxindole

17630-75-0
Laxagetten 4,4'-diacetoxydiphenylpyridylemethane 18869-73-3
3,3-Diallyl-1-phenyl-2-indolinone 19048-20-5

5-Bromo-2-oxindole

20870-78-4

5-Nitro-2-oxindole

20870-79-5
3-Allyl-3-(2-hydroxypropyl)-1-phenyl-2-indolinone 20870-57-9
3,3-Bis(2-hydroxypropyl)-1-phenyl-2-indolinone 20870-64-8
5-Chlorooxindole 25369-33-9
3-(Propylimino)-2-indolinone 26000-55-5
Indoprofen 31842-01-0
Oxindolylalanine 32999-55-6
3-Hydroxy-3-acetonyl-2-oxindole 33417-17-3
3-(Phenylimino)-2-indolinone 33828-98-7
Gardneramine 34274-91-4
3-Methyl-3-phenyl-1-piperidinomethylindolin-2-one maleate 37129-45-6
7-Benzoyl-2-oxindole 51135-38-7
3-Acetonyl-3-hydroxy-1-methyl-2-indolinone 3-oxime 51797-42-3
3-Hydroxy-3-phenacyloxindole 52552-33-7
Cofisatin 54063-34-2
Sulisatin 54935-04-5
3-Methyl-3-piperidinooxindole 55490-24-9
6-Chlorooxindole 56341-37-8

6-Fluorooxindole

56341-39-0

5-Fluoro-2-oxindole

56341-41-4
1-Valeryl-2-indolinone 57989-34-1
2-Indolinone-3-spiro-2'-(N-ethylpyrrolidine) 59022-44-5
2-Indolinone-3-spiro-4'-(N-ethylpiperidine) 59022-55-8
7-Methyl-2-indolinone-3-spiro-4'-(N-ethylpiperidine) 59022-56-9
2-Indolinone-3-spiro-3'-(N-ethylpyrrolidine) 59022-46-7
(p-Morpholinoethoxyphenyl)-1-tetrahydro-4,5,6,7-oxindole 67019-69-6
2-Indolinone-3-spiro-2'-(N-methylpiperidine) 69226-42-2
Nofedone 70096-13-8

5,6-Difluorooxindole

71294-07-0
5-Bromo-1-(diethylaminomethyl)-3,3-di-p-tolyl-2-indolinone 75472-67-2
5-Bromo-3,3-di-p-tolyl-1-(morpholinomethyl)-2-indolinone 75472-68-3
3-Acetonyl-5-bromodioxindole 76325-66-1
1-Pyrrolidinomethyl-3-(2-naphthyloxyacetylhydrazono)indolin-2-one 81215-50-1
5-Acetyl-3,3-diphenyl-1-(morpholinomethyl)-2-indolinone 81252-98-4
3,3-Diphenyl-5-methoxy-1-(piperidinomethyl)-2-indolinone 81252-99-5
25-Oxindolyl-ala-glucagon 83874-24-2
3-(5-Phenyl-1,3,4-oxadiazol-2-ylimino)-2-indolinone 84640-80-2
5-Methyl-3-(5-phenyl-1,3,4-oxadiazol-2-ylimino)-2-indolinone 84640-91-5
5-Chloro-3-(5-phenyl-1,3,4-oxadiazol-2-ylimino)-2-indolinone 84640-85-7
1,3-Bis(piperidinomethyl)-3-(p-bromophenyl)-2-indolinone 88323-52-8
1,3-Bis(morpholinomethyl)-5-methyl-3-phenyl-2-indolinone 88323-49-3

Methyl 2-oxindole-4-carboxylate

90924-46-2
Ropinirole hydrochloride 91374-20-8
5-Bromo-N,O-dibutyryldioxindole 99304-35-5
5-Bromo-O-acetyldioxindole 99304-36-6
7-Chloro-O-acetyldioxindole 99304-32-2
7-Chlorodioxindole 99304-29-7
N,O-Dipropionyldioxindole 99304-33-3
3-(Pyridyl-2-methyl)-5-bromodioxindole 99304-31-1
5-Methyl-N,O-dipropionyldioxindole 99304-34-4
5-Bromo-N,O-dipropionyldioxindole 99313-70-9

6-Bromo-2-oxindole

99365-40-9
Indolidan 100643-96-7
3-Hyroxy-3-(2-nitropropyl)-2-indolinone 101651-81-4
3-Hydroxy-3-(2-aminopropyl)-2-indolinone 101651-80-3
Pazinaclone 103255-66-9
Linopirdine 105431-72-9
3-Acetonyl-3-hydroxy-1-methyl-2-indolinone acetate 3-oxime 107864-74-4
Ziprasidone hydrochloride 138982-67-9
1-Methyl-3-(1-hexynyl)-3-hydroxy-2-indolinone 149916-73-4
3-(1-Hexynyl)-3-hydroxy-5-nitro-2-indolinone 149916-74-5
3-(1-Hexynyl)-3-hydroxy-2-indolinone 149916-72-3
3-((m-methylphenoxyacetyhdrazono)-2-indolinone 154910-41-5
3-Aminomethylene-5-nitrooxindole 159212-49-4
3-Aminomethylen-5-aminooxindole 159212-54-1
3-Methyl-5-aminooxindole 159212-53-0
Semaxanib 194413-58-6

Methyl 2-oxindole-5-carboxylate

199328-10-4

4,6-Difluorooxindole

247564-57-4

SALES SPECIFICATION

APPEARANCE

 off-white crystalline powder
ASSAY (G.C)

98.0% min

MOISTURE (K.F.)

0.5% max

LOSS ON DRYING

1.0% max
TRANSPORTATION
PACKING 25kgs in drum
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XN, Risk Phrases: 22, Safety Phrases: