1-METHYL PIPERAZINE

PRODUCT IDENTIFICATION

CAS NO.

109-01-3

1-METHYL PIPERAZINE

EINECS NO. 203-639-5
FORMULA C5H12N2
MOL WT. 100.16

H.S. CODE

2933.59

TOXICITY

Oral rat LD50: 2830
SYNONYMS N-Methyl piperazine; 4-Methylpiperazine;
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE Clear, Colourless liquid
MELTING POINT -6 C
BOILING POINT 138 C
SPECIFIC GRAVITY

0.903

SOLUBILITY IN WATER Miscible
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS Health: 2; Flammability: 2; Reactivity: 0

REFRACTIVE INDEX

1.4655
FLASH POINT

42 C

STABILITY

Stable under ordinary conditions

GENERAL DESCRIPTION & APPLICATIONS

Piperazine is a heterocyclic compound containing four carbon atoms and two of nitrogen at 1,4 position ( als called 1,4-hexahydropyrazine). It is a deliquescent crystalline compound melting at 105 C; soluble in water, alcohol, glycerol, and glycols. It is used as a main ingredient of anthelmintics used to treat intestinal roundworms (ascariasis) infection in human and  poultry and to treat pinworms (enterobiasis; oxyuriasis) by altering cell membrane permeability and causing hyperpolarization of the membrane. Piperazine is a main moiety in psychoactive drugs. Certain piperazine derivatives are suspected of ecstasy substitutes. Benzylpiperazine is bannaed in many countries. Benzylpiperazine  has been used as a anthelmintic (antiparastic effect). Nitrogen in piperazine ring plays an important role in biological research and drug manufacturing industry including the preparation of anthelmintic, antiallergenic, antibacterial, antihistamic, antiemetic and antimigraine agents. The piperazine ring and piperazine derivatives are important cyclic components in industrial field as raw materials for hardener of epoxy resins, corrosion inhibitors, insecticides, accelerators for rubber, urethane catalysts and antioxidants.  N-Methyl piperazine is used as an intermediate for antibiotics (quinolones) and pharmaceuticals (e.g antihistamines and tranquillisers). It is also used for the production of agrochemicals, surfactants, dyestuffs, pigment and other organic chemical compounds.
SALES SPECIFICATION

APPEARANCE

Clear, Colourless liquid

PURITY

99.0% min

BOILING POINT

134 - 138 C

MOISTURE

0.5% max

INDIVIDUAL IMPURITY

0.2% max (Piperazine, Di-Methyl Piperazine and etc)

TRANSPORTATION
PACKING
180kgs in drum
HAZARD CLASS 3 (Packing group : II)
UN NO. 1993
OTHER INFORMATION