alpha-KETOGLUTARIC ACID

PRODUCT IDENTIFICATION

CAS NO. 328-50-7

alpha-KETOGLUTARIC ACID

EINECS NO.

206-330-3

FORMULA C5H6O5
MOL WT. 146.10

H.S. CODE

2922.49
SMILES

 

TOXICITY

 

SYNONYMS 2-Ketoglutaric acid; 2-Oxopentanedioic acid;
2-Oxoglutamate; 2-Oxoglutaric acid; Oxoglutaric acid;

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

White solid

MELTING POINT

113 - 115 C

BOILING POINT  
SPECIFIC GRAVITY

 

SOLUBILITY IN WATER Soluble
pH 1.5 (50 g/l aq. soultion)
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

Health: 2; Flammability: 1; Reactivity: 0

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY

Stable under ordinary conditions. Moisture, light sensitive.

GENERAL DESCRIPTION

Glutaric acid (Pentanedioic Acid)is a dicarboxylic acid with five carbon atoms, occurring in plant and animal tissues. Glutaric acid is found in the blood and urine. Alpha-ketoglutaric acid, a derivative of glutaric acid which has a ketone group on the carbon atom next to the acid group,  is produced from glutamate in amino group and found as an intermediate in the  Krebs cycle in the body. In industrial field, ketoglutaric acid exhibits typical carboxyl group chemistry useful in a variety of industrial applications. It is a white crystalline solid having has the lowest melting point among dicarboxylic acids (98 C). It is very soluble in water and the solution is a medium strong acid. The molecular structure of odd carbon number is also useful to decrease polymer elasticity. Glutaric acid is used in the production of polyester polyols, polyamides, ester plasticizers and corrosion inhibitors. It is used in the synthesis of pharmaceuticals, surfactants and metal finishing compounds. Food grade alpha-ketoglutaric acid is used in dietary supplements to improve protein synthesis.
SALES SPECIFICATION (USP)

APPEARANCE

white to off-white crystalline powder

ASSAY

99.0% min

MELTING POINT

112 - 115 C

HEAVY METALS

10ppm max

LOSS ON DRYING

0.5% max

As

3ppm max

TRANSPORTATION
PACKING
25kgs in fiber drum
HAZARD CLASS Not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 37/38-41, Safety Phrases: 26-37/39