VERATROLE

PRODUCT IDENTIFICATION
CAS NO. 91-16-7

VERATROLE

EINECS NO. 202-045-3
FORMULA C6H4(OCH3)2
MOL WT. 138.17

H.S. CODE

 2909.30.2000

TOXICITY

 Oral rat LD50: 890 mg/kg
SYNONYMS 1,2-Dimethoxybenzene; o-Dimethoxybenzene; Veratrole;

Brenzkatechindimethylether; Catechol dimethyl ether; Dimethylether pyrokatechinu; O,O-Dimethyl catechol; Pyrocatechol dimethyl ether; Synthol; Veratrol;

SMILES

c1(c(cccc1)OC)OC

CLASSIFICATION

Flavors and Fragrances

EXTRA NOTES

 FEMA No. 3799
1,2-Dimethoxybenzene, commonly known as veratrole, is an organic compound with the formula C6H4(OCH3)2. It is a colorless liquid, with a pleasant odor and slight solubility in water. It is the dimethyl ether derived from pyrocatechol.

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE clear liquid
MELTING POINT 15 C
BOILING POINT 206 - 207 C
SPECIFIC GRAVITY 1.055 - 1.085
SOLUBILITY IN WATER Slightly soluble (soluble in alcohol and ether)
pH  
VAPOR DENSITY  

AUTOIGNITION

  

NFPA RATINGS

 Health: 2 Flammability: 2 Reactivity: 0

REFRACTIVE INDEX

  
FLASH POINT

87 C

STABILITY Stable under ordinary conditions. Light, air sensitive.

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Veratrole

Wikipedia Linking - 1,2-Dimethoxybenzene

Google Scholar Search - Veratrole

Drug Information Portal (U.S. National Library of Medicine) - Veratrole

PubChem Compound Summary - Veratrole

Chemical Entities of Biological Interest (ChEBI) - Veratrole

http://www.ncbi.nlm.nih.gov/ - Veratrole

EPA - Substance Registry Services - Veratrole

Local:
Guaiacol is the methyl ether of pyrocatechol. It is a main constituent of creosote obtained from wood tar (mainly beech) by distillation mostly between 203 and 220 C. It is synthesized from anisole also. The dimethyl ether of pyrocatechol is called veratrol. They and their derivatives are used as an external antiseptic, expectorant, gastric sedative, deodorant, and as a parasiticide. Methoxyphenols are used in manufacturing stabilizers and antioxidants for plastics and rubbers.They are also used in analgesics, local anesthetic, flavorings, biocides, antiseptics. 2-Methoxyphenol is used in manufacturing vanillin and other flavorings.

GENERAL DESCRIPTION OF DIHYDROXYBENZENE - There are three isomeric compounds of dihydroxybenzene molecule structure, which all have traditional names respectively. The ortho (1,2) isomer is called catechol (Also known as catechin; pyrocatechol; pyrocatechuic acid), which forms clear crystals used as a photographic developer in solution and as a starting material to produce synthetic catecholamines which have important physiological effects as neurotransmitters and hormonesany (such as epinephrine,  adrenaline, norepinephrine, and dopamine). The meta (1,3) isomer is resorcinol (also known as resorcin), which forms clear needle crystals used in the production of diazo dyes and plasticizers. It is produced by sulfonating benzene with fuming sulfuric acid and fusing the resulting benzenedisulfonic acid with caustic soda. Resorcinol is used in resins as an UV absorber. It is used in manufacturing fluorescent and leather dyes and adhesives. Reaction with formaldehyde produces resins (resorcinol formaldehyde resins) used to make rayon and nylon. It is used as a pharmaceutical to treat acne and other greasy skin conditions in combination with other acne treatments such as sulfur. It is used as an anti-dandruff agent in shampoo and sunscreen cosmetics. It is also used as a chemical intermediate to synthesis pharmaceuticals and other organic compounds. The para (1,4) isomer is hydroquinone (also known as quinol), which forms clear prisms used as a photographic reducer and developer (except in color film). It is formed in large quantities by chemical reduction of benzoquinone. This compound is a general-purpose inhibitor, stabilizer, antioxidant, and intermediate. One of the major uses of hydroquinone is as an intermediate to make other inhibitors, stabilizers, antioxidants, agricultural chemicals, and dyes. Resorcinol and its derivatives are used in resins as UV absorbers. They are used in manufacturing fluorescent and leather dyes and adhesives (resorcinol formaldehyde resins). They are used as pharmaceuticals to treat acne and other greasy skin conditions in combination with other acne treatments such as sulfur. They are used as an anti-dandruff agent in shampoo and sunscreen cosmetics.
SALES SPECIFICATION

APPEARANCE

 clear liquid
ASSAY

99.0% min

MOISTURE 0.2% max
TRANSPORTATION
PACKING
 
HAZARD CLASS Not regulated
UN NO.  
SAFETY INFORMATION

HAZARD OVERVIEW

Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.

GHS

 

SIGNAL WORD

Warning

PICTOGRAMS

HAZARD STATEMENTS

H302-H312-H332

P STATEMENTS

P310

EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

20/21/22

SAFETY PHRASES

23

PRICE INFORMATION