SODIUM CYCLAMATE

PRODUCT IDENTIFICATION

CAS NO. 139-05-9

SODIUM CYCLAMATE

EINECS NO. 205-348-9
FORMULA C6H11NHSO3Na
MOL WT. 201.22

H.S. CODE

2921.30.5000

TOXICITY

Oral Rat LD50: 1280mg/kg
SYNONYMS Sodium cyclohexanesulfamate;
Cyclohexanesulfamic acid monosodium salt; Assugrin; Asugryn; Cyclohexylsulfamic acid monosodium salt; Hachi-sugar; Ibiosuc; Sodium cyclohexyl amidosulfate; Sodium cyclohexyl sulfamate; Sodium cyclohexylsulfamidate; Sodium N-cyclohexylsulfamate; N-Cyclohexylsulphamic acid sodium salt; Sodium sucaryl; Suessette; Suestamin; N-Cyklohexylsulfamat sodny; Natraiumcyclohexylamidosulfat; Other RN: 53170-91-5, 61373-78-2
SMILES C1(NS(=O)(=O)[O-])CCCCC1.[Na+]

CLASSIFICATION

Sweetener, Sulfamate

EXTRA NOTES

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white crystals
MELTING POINT >300 C
BOILING POINT  
SPECIFIC GRAVITY

 

SOLUBILITY IN WATER

200 g/l

SOLVENT SOLUBILITY

Insoluble in ether and benzene
pH 5.5 - 7.0
VAPOR DENSITY

 

REFRACTIVE INDEX

 

NFPA RATINGS

Health: 1 ; Flammability: 0 ; Reactivity: 0

AUTOIGNITION

 

FLASH POINT

> 200 C

STABILITY Stable under normal conditions.

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - Sodium cyclamate

PubChem Compound Summary - Sodium cyclamate

IPCS INCHEM -  Sodium cyclamate

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Sodium cyclamate

http://www.ebi.ac.uk/ -  Sodium cyclamate

http://www.ncbi.nlm.nih.gov/ -  Sodium cyclamate

Human Metabolome Database - Sodium cyclamate

Material Safety Data Sheet

http://journals.sfu.ca/ Sweeteners permitted in the European Union: safety aspects

Cyclamate (E952): Three different compounds are referred to as cyclamates: cyclamic acid, calcium cyclamate and sodium cyclamate. Cyclamates, whether in the form of sodium cyclamate or calcium cyclamate, are stable in heat and cold and have good shelf-life. The stability and solubility in water facilitate the use of cyclamates in foodstuffs and beverages. Cyclamate has the lowest sweetening power of the intense sweeteners, but combined with other intense sweeteners, a synergistic effect masks the aftertaste associated with the use of a single sweetener. The mixture of 10 parts cyclamate and one part of saccharin was widely used in foods and beverages during the 1960s. In 1969, however, cyclamate was prohibited in many countries because bladder tumours were found in rats fed with the 10:1 cyclamate saccharin mixture (33). Since then, several additional toxicity and carcinogenicity studies have been conducted with cyclamate, the cyclamate saccharin mixture and cyclamate meta- Safety aspects of sweeteners metabolite cyclohexylamine (CHA).

Local:
Sodium Cyclamate is a white, odorless, free flowing crystalline powder used as a nonnutritive low-calorie sweetener choice ( but prohibited in some countries due to possible carcinogenic effects of its metabolic products). It is freely soluble in water. It is known about 30 times sweeter than sucrose.

SALES SPECIFICATION (NF-13, BP93)

APPEARANCE

white crystals

ASSAY

98.5% - 101.0%

pH

5.5 - 7.0

FREE ACID

0.3% max

SULFATE

0.1% max

CYCLOHEXYLAMINE

1ppm max

DICYCLOHEXYLAMINE

10ppm max

ANILINE

1ppm max

As

3ppm max

Pb

1ppm max

Se

30ppm max

HEAVY MERALS

10ppm max

LOSS ON DRYING

0.5% max

ABSORPTION

0.1 max (270nm)

TRANSPORTATION
PACKING
HAZARD CLASS  
UN NO.

Not Regulated.

SAFETY INFORMATION

HAZARD OVERVIEW

Harmful if swallowed. May cause eye, skin, and respiratory tract irritation. OSHA Hazards:Target Organ Effect, Harmful by ingestion. Target Organs: Liver, Kidney, Bladder, Pancreas., Testes., Cardiovascular system.

GHS

 

SIGNAL WORD Warning

PICTOGRAMS

HAZARD STATEMENTS

H302

P STATEMENTS

P301+ P312
EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

22

SAFETY PHRASES

24/25-45

PRICE INFORMATION