RIBOFLAVIN

PRODUCT IDENTIFICATION
CAS NO.

83-88-5

RIBOFLAVIN

EINECS NO. 201-507-1
FORMULA C17H20N4O6
MOL WT. 376.37

H.S. CODE

  

TOXICITY

 
SYNONYMS 7,8-Dimethyl-10-ribitylisoalloxazine;
Flavin; Lactoflavine; 3,10-Dihydro-7,8-dimetyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl] benzo[g]pteridine-2,4-dione; Ovoflavin; Riboflavin; Vitamin B2; Zinvit-G;
DERIVATION

 

CLASSIFICATION

NATURAL COLORANT / VITAMINS /

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE yellow to orange crystalline powder
MELTING POINT 280 - 290 C (Decomposes)
BOILING POINT

 

SPECIFIC GRAVITY

 

SOLUBILITY IN WATER

Slightly soluble

SOLVENT SOLUBILITY

Soluble in dilute alkaline solutions, insoluble in alcohol

pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY

Stable under ordinary conditions. Light sensitive.

APPLICATIONS
Riboflavin: A member of the vitamin B complex (water-soluble) including thiamine (vitamin B1), riboflavin (vitamin B2), riboflavin 5'- phosphate, nicotinic acid, Vitamin B6 Group (Pyridoxine, pyridoxal, pyridoxamine), panthothenic acid (vitamin B3 or vitamin B5), inositol, p-aminobenzoic acid, biotin (vitamin B7), folic acid (vitamin B9), and vitamin B12 (cobalamins). Riboflavin is a water-soluble yellow to orange fluorescent pigment with the chemical structure of substituted isoalloxazine ring system linked to ribitol. (Flavin is a water-soluble compound containing the isoalloxazine nucleus which is characterized by a yellow color and intense green fluorescence when oxidized. Ribitol is a sugar alcohol formed by reduction of the carbonyl group of ribose). Riboflavin is essential to human nutrition as a component of two coenzymes;  flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) of flavoproteins, that are associated with several respiratory enzymes in plants and animals as electron carriers, important in biochemical oxidations and reductions. The deficiency of riboflavin results in the disease beriberi. The phosphoric acid esters of riboflavin are administered orally or parenterally in the treatment of dietary riboflavin deficiency.
  • Riboflavin 5'-Phosphate (Flavin Mononucleotide, FMN): serving as an electron carrier in biochemical oxidations and reductions; acting as a coenzyme for a number of oxidative enzymes, including NADH dehydrogenase.
  • Riboflavin 5'-Phosphate sodium: the sodium salt of riboflavin 5'-phosphate; administered orally or parenterally in the treatment of dietary riboflavin deficiency.
  • Riboflavine 5'-Adenosine Diphosphate (Flavin Adenine Dinucleotide. FAD): serving as an electron carrier in biochemical oxidations and reductions; forming prosthetic group of many flavoprotein enzymes, including D-amino acid oxidase and xanthine oxidase; a coenzyme composed of riboflavin 5'-phosphate (FMN) and adenosine 5'-phosphate linked by a pyrophosphate bond.
  • Flavin Adenine Dinucleotide Sodium: the sodium salt of Riboflavine 5'-Adenosine Diphosphate ; administered orally or parenterally in the treatment of dietary riboflavin deficiency.

Molecular compounds of riboflavin

Product

CAS RN
Riboflavin 83-88-5
Toxoflavin 84-82-2
Riboflavin sodium phosphate 130-40-5
Flavin adenin dinucleotide 146-14-5
Riboflavin 5'-phosphate 146-17-8
Araboflavin 482-11-1
Riboflavin tetrabutyrate 752-56-7
2',3',4',5'-Tetraacetylriboflavin 752-13-6
Lumichrome 1086-80-2
Lumiflavin 1088-56-8
Riboflavin 5'-sulfate 1107-62-6
Griseoflavin 1403-70-9
8-Fluoro-8-demethylriboflavin 1691-79-8
1,5-Dihydroriboflavin-adenosine diphosphate 1910-41-4
Flavin-hypoxanthine dinucleotide 2466-56-0
Ethanol lumiflavin 3180-56-1
Formylmethylflavin 4250-90-2
8-Amino-8-demethylriboflavin 5178-05-2
1,5-Dihydroriboflavin 5'-(dihydrogen phosphate) 5666-16-0
7-Bromo-7-demethylriboflavin 5691-79-2
7-Methyl-8-ethylflavin 5720-14-9
7,8-Diethylflavin 5720-12-7
Galactoflavin 5735-19-3
Isoriboflavine 5984-80-5
Riboflavin 5'-monophosphate sodium salt dihydrate 6184-17-4
7-Chloro-7-demethylriboflavin 7146-48-7
Riboflavin, sodium salt 7681-29-0
Rubiflavin 11016-71-0
Aranoflavin A 11076-00-9
Aranoflavin B 11091-34-2
Riboflavin tetranicotinate 14984-66-8
Riboflavin 5'-pyrophosphate 14985-41-2
3-Methyllumiflavin 18636-32-3
5-Deazariboflavin 19342-73-5
Riboflavin-5'-monobutyrate 20704-80-7
10-(Carboxyethyl)flavin 20781-13-9
Carboxymethylflavin 21079-31-2
Flavinyltryptophan 21099-87-6
Riboflavin 5'-(dihydrogen phosphate) sodium salt 22251-85-0
5-Deazaflavin 26908-38-3
5'-D-Riboflavin-D-glucopyranoside 26909-04-6
3-Carboxymethylriboflavin 28714-80-9
3-Methylriboflavin 28721-76-8
8-Demethyl-6-methylriboflavin 5'-(dihydrogen phosphate) 28848-42-2
7-Methyl-8-trifluoromethyl-10-(1'-D-ribityl)isoalloxazine 28956-72-1
2-Thioriboflavine 5'-monophosphate 28979-30-8
Resistoflavin 29706-96-5
Sorboflavin 33210-88-7
Theaflavin digallate 33377-72-9
Flavin mononucleotide semiquinone 34469-63-1
Hydroxymethylflavin 35847-78-0
Flavin semiquinone 35919-91-6
5-Deazariboflavin-5'-phosphate 36408-16-9
7,8-Didemethyl-8-hydroxy-5-deazariboflavin 37333-48-5
N(3)-Histidylriboflavin 37854-44-7
Flavin 1,N(6)-ethenoadenine dinucleotide 38628-24-9
Flavin-adenine dinucleotide phosphate 38716-27-7
8-Bromo-8-demethylriboflavin 40371-66-2
7-Chloro-7,8-didemethyl-8-ethylriboflavin 42782-52-5
8-Chloro-7,8-didemethyl-7-ethylriboflavin 42782-53-6
2-Thioriboflavin-adenosine diphosphate 43203-75-4
1,5-Dihydro-N(3)-carboxymethyllumiflavin 50635-52-4
Roseoflavin 51093-55-1
7-Bromo-7,8-didemethyl-8-ethylriboflavin 51541-32-3
8-Bromo-7,8-didemethyl-7-ethylriboflavin 51568-68-4
8-Hydroxymethylriboflavin 52134-62-0
S-Cysteinylriboflavin 52154-87-7
Furoflavin 52229-44-4
6-Hydroxyriboflavin-adenosine diphosphate 52301-43-6
2',3',4',5'-Tetrabenzoyl-5-acetyl-1,5-dihydroriboflavin 52492-58-7
Lyxoflavin 5'-monophosphate 53860-75-6
5-Deazariboflavin-5'-diphosphate 57818-88-9
Vitamin B2 aldehyde 59224-04-3
7-Bromo-7-demethylriboflavin 5'-(dihydrogen phosphate) 60697-31-6
2(4)-Imino-4(2)-amino-2,4-dideoxyriboflavin 61098-18-8
5-Deazalumiflavin 61696-29-5
Riboflavin permease 61970-05-6
8-Methylamino-riboflavin 62746-55-8
1-Deazariboflavin 64183-66-0
Coenzyme F420 64885-97-8
10-(4'-Chlorophenyl)-3-methylflavin 65626-87-1
8-Chlororiboflavin-adenosine diphosphate 68385-36-4
N(3)-Methyltetraacetylriboflavin 69447-57-0
8-Mercaptoriboflavin-adenosine diphosphate 71800-97-0
8-Mercaptoriboflavin 71800-64-1
8-Demethyl-8-mercaptoriboflavin 5'-(dihydrogen phosphate) 71800-98-1
8-Methoxyriboflavin 72680-49-0
Flavin N(6)-(N'-2,4-dinitrophenyl-6-aminohexyl)adenine 73121-99-0
Riboflavin-5'-monopalmitate 73130-89-9
8-Chloro-8-demethylriboflavin 5'-(dihydrogen phosphate) 73358-82-4
6-Thiocyanatoriboflavin 73647-56-0
6-Aminoriboflavin 73652-55-8
N(6)-Aminohexyl-flavin adenine dinucleotide 76748-73-7
Methyl-ethyl-monohydro-lumiflavin 78169-56-9
Cardiocrome 78623-42-4
Flavin adenine dinucleotide sodium 84366-81-4
7-Hydroxymethylriboflavin 86073-07-6
Riboflavin 3',5'-bisphosphate 86108-26-1
5-Deazaflavin 4,5-epoxide 86889-50-1
5'-Malonylriboflavin 88623-79-4
5'-Malonylriboflavin 88623-79-4
1,5-Dihydro-3-(3-sulfopropyl)lumiflavin 91385-12-5
8alpha-N-Imidazolylriboflavin 97219-10-8
4a,5-Dihydroriboflavine 101652-10-2
6-Azidoriboflavin 101760-83-2
6-Thiocyanatoriboflavin-adenosine diphosphate 101760-87-6
6-Azidoriboflavin-adenosine diphosphate 101760-85-4
6-Mercaptoriboflavin 101760-88-7
6-Mercaptoriboflavin-adenosine diphosphate 101760-90-1
4a,5-Dihydroriboflavine 5'-phosphate sodium salt 102338-88-5
Rubiflavin hydrochloride 102583-57-3
Riboflavin 5'-phosphorothioate 109637-87-8
4a,5-Epoxyethano-3-methyl-4a,5-dihydrolumiflavin 112076-30-9
10-(3',5'-Dimethylphenyl)-3-methylflavin 119237-63-7
10-(3',5'-Dichlorophenyl)-3-methylflavin 119237-62-6
N(5)-Ethyl-4a-hydroxy-3-methyl-4a,5-dihydrolumiflavin 129119-76-2
Rivicycline 130030-59-0
8-Thiocyanatoriboflavin 130574-30-0
Triflavin 133247-60-6
Rubroflavin 138749-63-0
8-(Methylsulfonyl)riboflavin-adenosine diphosphate 149091-08-7
Riboflavin 3'-sulfate 149634-99-1
SALES SPECIFICATION

BIBLIOGRAPHY

USP23 / BP93

APPEARANCE

 yellow to orange crystalline powder

IDENTIFICATION

Complies (Test A, B)

ASSAY

 98.0 ~102.0%

OPTICAL ROTATION

+56.5° ~ +59.5°

LOSS ON DRYING

 1.5% max

RESIDUE ON IGNITION

0.2% max

IMPURITY

Complies
TRANSPORTATION
PACKING
25kgs in Fiber Drum
HAZARD CLASS Not regulated
UN NO.  
OTHER INFORMATION