N-ACETYL-GLUCOSAMINE

PRODUCT IDENTIFICATION
CAS NO. 7512-17-6

N-ACETYL-GLUCOSAMINE 

EINECS. 233-115-1
FORMULA C8H15NO6
MOL WT. 221.21

H.S. CODE

 2932.99.9090

TOXICITY

 

SYNONYMS

 NAG; GlcNAc; N-Acetyl-D-glucosaminide; Acetylglucosamine;
2-Acetamido-2-deoxy-D-glucopyranose; N-乙酰氨基葡萄糖; N-Acetylchitosamine; 2-Acetamido- 2-deoxy- alpha-glucopyranose; N-Acetyl-D-glucosamine; 2-(acetylamino)-2-deoxy-D-glucose; 2-Acetamido-2-deoxy-D-glucose; N-Acetylglucosamine; N-Acetyl-beta-D-glucosamine; N-Acetyl-beta-D-glucosaminide; Other RN: 134-61-2, 7132-76-5, 98632-70-3, 173382-53-1, 948887-87-4
SMILES

N([C@@H]1[C@H]([C@@H]([C@@H](CO)O[C@H]1O)O)O)C(C)=O

CLASSIFICATION

 

EXTRA NOTES

  

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE white crystalline powder
MELTING POINT

195 - 205 C

BOILING POINT

 

SPECIFIC GRAVITY

 

SOLUBILITY IN WATER soluble
pH 7.0 - 8.5
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY Stable under ordinary condiions

GENERAL DESCRIPTION & APPLICATION
Glucosamine is the most abundant naturally occurring amino sugar in which one or more nonglycosidic hydroxyl groups are replaced by an amino or substituted amino group. Glucosamine is a glucose substituted at the 2 position. It is present in peptidoglycans and  variety of complex polysaccharides such as blood group substances. It is generally acetylated (N-acetylglucosamine). It is the basic structural unit of chitin which is a linear unbranched homopolymer composed of N-acetyl-D-glucosamine residues in beta-linkage (1,4) like cellulose. Chitin is the principal constituent of arthropod exoskeletons to cover the surface of the body, found mainly in crab, lobster or shrimp shell. Chitin is also found in the cell walls of some fungi. Muramic acid is a compound consisting of glucosamine and lactic acid joined by an ether linkage. It is the characteristic polysaccharide composing bacterial cell walls. Chitosan is the de-acetylation form of chitin; a polysaccharide composed of repeating glucosamine units. It is used to absorb heavy metals in water treatment. Chondroitin is a glycosaminoglycan composed of a sulfated (C-4 or C-6) N-acetylgalactosamine residue linked to a glucuronic acid residue. It is the It consists of repeating disaccharide units. It is abundant in connective tissues, particularly in the ground substance of   blood vessels, bone, and cartilage. Chondroitin sulfate A is sulfated on C-4 position and called also chondroitin 4-sulfate to dominate the position of the sulfate group on the sugar, while Chondroitin sulfate C is chondroitin 6-sulfate. Chondroitin sulfate B is another name of dermatan sulfate which  is sulfated on the C-4 position but also the C-5 of the uronic acid is under the epimerisation of glucuronic acid to iduronic acid. Glucosamine and chondroitin sulfate are being tested for potential benefit in osteoarthritis. They are stabilizd with hydrochloride or sulfur to be used as dietary or nutritional supplements. Glucosamine is believed to contribute to the pain relief of cartilage and structure rebuilding of cartilage in the joint. N-acetyl-glucosamine is a building block of connective tissues to hold cells together. It is reported that NAG plays role in mucous membranes such as in the digestive also. NAG layer plays role in tissue rebuilding and the digestive tract.
SALES SPECIFICATION

APPEARANCE

 white crystalline powder
ASSAY
98.0% min
HEAVY METALS

10ppm max

ARSENIC

1ppm max

IRON

10ppm max

CHLORIDE

1.0% max

MELTING POINT

195 - 205 C

RESIDUE ON IGNITION

0.1% max

SPECIFIC ROTATION

+39° ~ +43°

LOSS DRYING

0.5% max
TRANSPORTATION
PACKING

 

HAZARD CLASS not regulated
UN NO.  
OTHER INFORMATION