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METHYL SALICYLATE
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PRODUCT IDENTIFICATION |
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| CAS NO. | 119-36-8 |
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| EINECS NO. | 204-317-7 | |
| FORMULA | C6H4(HO)COOCH3 | |
| MOL WT. | 152.15 | |
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HS CODE |
2918.23 | |
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TOXICITY |
Oral rat LD50: 887 mg/kg | |
| SYNONYMS | Synthetic Wintergreen Oil; Methyl Hydroxybenzoate; | |
| Betula Oil; O-hydroxybenzoic Acid Methyl Ester; Gaultheria Oil; Methyl Sweet Birch Oil; O-hydroxybenzoate; 2-(Methoxycarbonyl)Phenol; 2-carbomethoxyphenol; Linsal; Methylester Kyseliny Salicylove (Czech); Salicylic Acid, Methyl Ester; o-Anisic acid | ||
| SMILES | 2-HydroxyBenzoic acid; Salicylic acid (69-72-7 ) | |
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | Clear liquid to yellowish or reddish oily liquid | |
| MELTING POINT | -8.3 C | |
| BOILING POINT | 222 C | |
| SPECIFIC GRAVITY | 1.179-1.184 | |
| SOLUBILITY IN WATER | Sparingly soluble | |
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SOLVENT SOLUBILITY |
Soluble In Ether, Glacial Acetic Acid | |
| pH | ||
| VAPOR DENSITY |
5.24 | |
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AUTOIGNITION |
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NFPA RATINGS |
Health: 1; Flammability: 1; Reactivity: 0 | |
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REFRACTIVE INDEX |
1.535 - 1.538 | |
| FLASH POINT |
96 C | |
| STABILITY | Stable under ordinary conditions | |
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APPLICATIONS |
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| Methyl Salicylate is used in flavoring for foods, candies, beverages and pharmaceuticals. It is used as a perfumery like magnolia, meadowsweet, root beer. It is also an odorant, perfume and ultraviolet absorber in cosmetics. This compound is used in medicine mainly for dephlogistication, analgesia. It is used in liniments and ointments for the relief of pain of lumbago, sciatica and rheumatics | ||
| SALES SPECIFICATION | ||
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BP2000/USP25/CP2000 |
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APPEARANCE |
Colorless or light pale yellow liquid with Characteristic odor |
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ASSAY |
99.0 - 100.5% |
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PHENOL |
100ppm max |
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HEAVY METALS |
20ppm max |
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| ACIDITY |
0.4% max |
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| TRANSPORTATION | ||
| PACKING |
25kgs in Drum , 230kgs In Drum | |
| HAZARD CLASS | Not regulated | |
| UN NO. | ||
| OTHER INFORMATION | ||
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Methyl Ester of Salicylic Acid
easily turns to darken color in exposure
to air. FEMA #: 2745 |
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GENERAL DESCRIPTION OF SALICYLIC ACID |
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Salicylic Acid is a white crystalline powder or needle-shaped crystals with
sweetish taste; soluble in acetone, ether, alcohol, boiling water, benzene and
turpentine, sparingly soluble in chloroformbenzene, slightly soluble in water;
melts at 158°C. The sodium salt form (sodium salicylate) is common commercially,
prepared from mainly sodium phenolate with carbon dioxide under heating and
pressure. It contains both a hydroxyl and a carboxyl group, which react with
either an acid or an alcohol. The carboxyl group forms esters with alcohols;
e.g. methyl salicylate is formed with methanol, which used in food flavorings
and preservatives; menthyl salicylate is formed with methanol, which is used in
suntan lotions. The hydroxyl group reacts with acetic acid to form
acetylsalicylic acid (called aspirin) which is the most widely common antiseptic
and antipyretic agent. Phenyl salicylate (called salol) is formed with phenol,
which is also used as an antiseptic and antipyretic agent. The sodium salt
(Sodium salicylate), a shiny white powder, is used for antiseptics preparations
and as a preservative. In addition to its analgesic and antipyretic properties,
salicylic acid possesses keratinolytic properties and fungicidal properties. It
ans its derivatives are used in the treatment of hyperkeratotic, dandruff,
ichthyosis and psoriasis as well as in the treatment of fungal skin infections
such as tinea. Para-Aminosalicylic acid (abbreviated PAS and PASA) is an
analogue of para-aminobenzoic acid (abbreviated PABA) that inhibits folic acid
synthesis in Mycobacterium tuberculosis and is bacteriostatic, inhibits growth
and multiplication of the tubercle bacillus. Para-Aminosalicylic acid and its
sodium salt (sodium p-Aminosalicylate) are bacteriostatic against mycobacteria
and used in the treatment of tuberculosis; administered orally. Brand names are
Tubasal, Nemasol Sodium and etc. Aminosalicylic acids are pharmaceutically
active ingredients including anti-infectives against colds, flu, or other virus
infections. Mesalamine (5-aminosalicylic acid, abbreviated 5-ASA) an active
metabolite of sulfasalazine, used to treat inflammation of the rectum and lower
colon, mild to moderate ulcerative colitis proctosigmoiditis, and proctitis. Para-Aminosalicylic acid
(4-hydroxybenzoic
acid) is used as an intermediate of bacteriostatic agent
specially for parabens (alkyl esters of
p-hydroxy benzoic acid) which used in food and personal care products as a preservative.
It is applied in the production of liquid crystal polymers.
It is also used as an intermediate of dyes, insecticides,
pharmaceutical, pesticides and
other chemical compounds.
Salicylic Acid and its derivatives are important for the preparation of other
pharmaceutical products, dyes, flavours, and preservatives.
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