LACTIC ACID

PRODUCT IDENTIFICATION

CAS NO

50-21-5, 79-33-4 (L), 10326-41-7 (D)

LACTIC ACID

EINECS NO. 200-018-0
FORMULA

CH3CH(OH)COOH

MOL WT.

90.08

H.S. CODE

2918.11.1000

TOXICITY

Oral rat LD50: 3543 mg/kg
SYNONYMS 2-Hydroxypropanoic acid; Lactic acid;
1-Hydroxyethanecarboxylic acid; Ethylidenelactic acid; alpha-Hydroxypropionic Acid; Milchsäure (Dutch); ácido lactico (Spanish); Aacide lactique (French);
Acidum lacticum; Aethylidenmilchsaeure; DL-Lactic acid; Ethylidenelactic acid; Other RN: 152-36-3, 598-82-3
SMILES C([C@@H](C)O)(O)=O

CLASSIFICATION

Food acidity regulator, Preservative, Plant growth regulator

EXTRA NOTES

A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation.
Conversion to glucose via gluconeogenesis in the liver and release back into the circulation
FEMA No. 2611 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE Colorless to slightly yellow, syrupy liquid
MELTING POINT 17 C
BOILING POINT 122 C
SPECIFIC GRAVITY 1.209
SOLUBILITY IN WATER Miscible
SOLVENT SOLUBILITY Soluble in Alcohol, Furfurol, Glycerol
pH  
log P

-0.72 (octanol-water)

REFRACTIVE INDEX

 

NFPA RATINGS

Health: 2 Flammability: 1 Reactivity: 1

AUTOIGNITION

 

FLASH POINT

112 C

STABILITY Stable under ordinary conditions

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - Lactic acid

PubChem Compound Summary - Lactic acid

Drug Bank -  Lactic acid

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Lactic acid

http://www.ebi.ac.uk/ -  Lactic acid

http://www.ncbi.nlm.nih.gov/ -  Lactic acid

Human Metabolome Database - Lactic acid

Material Safety Data Sheet

Local:
Lactic acid (chemically, alpha or 2-Hydroxypropionic acid) takes roles in metabolic processes in the body; in red blood and in skeletal muscle tissues as a product of glucose and glycogen metabolism. Lactic acid is an "alpha hydroxy acid: which has a hydroxyl group on the carbon atom next to the acid group. If the hydroxy group is on the second carbon next to the acid group, it is called beta-hydroxy acid. Lactic acid is converted in vivo to pyruvic acid (an alpha keto acid) which occurs as an intermediate product in carbohydrate and protein metabolism in the body. Lactic acid occurs as two optical isomers since the central carbon atom is bound to four different groups; a dextro and a levo form ( or an inactive racemic mixture of the two); only the levo form takes part in animal metabolism. Lactic acid is present  in sour milk and dairy products such as cheese, yogurt, and  koumiss, leban, wines.  Lactic acid causes tooth decay since lactic acid bacteria operates in the mouth. Although it can be prepared by chemical synthesis, production of lactic acid by fermentation of glucose and other sugar substances in the presence of alkaline such as lime or calcium carbonate is a less expensive method. The six-carbon glucose molecule is broken down to two molecules of the three-carbon compounds (lactic acid), during this anaerobic condition. Synthetic lactic acid is used commercially in tanning leather and dyeing wool; as a flavouring agent and preservative in food processing and carbonated beverages; and as a raw material in making plastics, solvents, inks, and lacquers; as a catalyst in numerous chemical processes. Lactic Acid is available as aqueous solutions of various concentrations, usually 22 - 85 percent (pure lactic acid is a colourless, crystalline substance.) Some examples of lactates (salts or esters of lactic acid) are:

  • Ammonium Lactate (NH4C3H5O3, CAS RN: 515-98-0): clear to yellow, syrupy liquid used in in electroplating, in finishing leather and as humectant for food, pharmaceutical, and cosmetics.
  • Butyl Lactate (CH3CHOHCOOC4H9, CAS RN:138-22-7): a clear liquid: nontoxic, miscible with many solvents; used as a solvent for varnish, lacquers, resins and gums, used in making paints, inks, dry cleaning fluid, flavoring and as a chemical intermediate.
  • Calcium Lactate Pentahydrate [Ca(C3H5O3)2·5H2O, CAS RN: 814-80-2] : white crystals; soluble in water; used as a calcium source; administered orally in the treatment of calcium deficiency; as a blood coagulant.
  • Ethyl Lactate   (CH3CHOHCOOC2H5, CAS RN: 97-64-3): clear liquid with mild odur; boiling point 154 C; miscible with alcohols, ketones, esters, and hydrocarbons as well as with water; used in pharmaceutical preparations, feed additive, as a flavoring ( odor description: sweet butter, coconut, fruity, creamy dairy, butterscotch) and as a solvent for cellulose compounds such as nitrocellulose, cellulose acetate, and cellulose ethers.
  • Magnesium Lactate Trihydrate [Mg(C3H5O3)2·3H2O, CAS RN: 18917-93-6 ]: white crystals with bitter taste; soluble in water, slightly soluble in alcohol; used in medicine and as an electrolyte replenisher.
  • Manganese Lactate Trihydrate [Mn(C3H5O3)2·3H2O]: pale red crystals; insoluble in water and alcohol; used in medicine.
  • Mercuric Lactate [Hg(C3H5O3)2]: poisonous white powder that decomposes when heated; soluble in water; used in medicine.
  • Methyl Lactate (CH3CHCHCOOCH3): clear liquid with mild odur; boiling point 145 C; miscible with alcohols, ketones, esters, and hydrocarbons as well as with water; used in pharmaceutical preparations, feed additive, as a flavoring and as a solvent for cellulose compounds such as nitrocellulose, cellulose acetate, and cellulose ethers.
  • Sodium Lactate (CH3CHOHCOONa, CAS RN: 72-17-3) clear to yellow, hygroscopic syrupy liquid; soluble in water; melting point 17 C; used in medicine, in antifreeze, and hygroscopic agent and as a corrosion inhibitor.
  • Zinc Lactate (Zn(C3H5O3)2·2H2O, CAS RN: 16039-53-5): white crystals; used as an additive in toothpaste and food; preparation of drugs.

EXAMPLES OF NATURALLY OCCURRING CARBOXYLIC ACIDS
(excluding fatty acids)

Pyruvic acid

Lactic Acid

Cholic acid

Nicotinic acid

PYRUVIC ACID

Lactic Acid

cholic acid

Nicotinic acid

metabolic intermediate

metabolic intermediate

from bile

vitamin B

 

Citric acid

Malic Acid

Biotin

Abietic acid

Citric acid

Malic Acid

Biotin

Abietic acid

in plants

in fruits

cell growth factor

pine rosin

SALES SPECIFICATION

FCC IV 80 GRADE

APPEARANCE

Clear to slightly yellow liquid

PURITY

80% min

CHLORIDE

20ppm max

SULFATE

0.01% max

RESIDUE ON IGNITION

0.1% max

Fe

10ppm max

As

1ppm max

HEAVY METALS

10ppm max

TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO. Not regulated
SAFETY INFORMATION

HAZARD OVERVIEW

OSHA Hazards: Irritant

GHS

 

SIGNAL WORD

Danger

PICTOGRAMS

HAZARD STATEMENTS

H315-H318-H338

P STATEMENTS

P-261-P280-P302 + P352-P305 + P351 + P338

EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

37/38

SAFETY PHRASES

41

PRICE INFORMATION