GLYCINE

PRODUCT IDENTIFICATION

CAS NO. 56-40-6

GLYCINE

EINECS NO. 200-272-2
FORMULA H2NCH2COOH
MOL WT.

75.07

H.S. CODE

2922.49

TOXICITY

Oral rat LD50 7930 mg/kg

SYNONYMS Aminoacetic Acid; Glycocoll; Athenon; Gly; G salt;
Iconyl; Monazol; glycosthene; p-Hydroxyphenylaminoacetic Acid; Aminoethanoic Acid; p-Hydroxyanilinoacetic Acid; para-Oxyphenyl Glycocoll; Sucre De Gelatine;
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE White crystals, Odorless
MELTING POINT 245 C (Decompose)
BOILING POINT

 

SPECIFIC GRAVITY

1.6

SOLUBILITY IN WATER 25g/100 ml

pH

5.97 (Isoelectric point)

VAPOR DENSITY

 

REFRACTIVE INDEX

 

AUTOIGNITION

 

NFPA RATINGS Health: 0 Flammability: 1 Reactivity: 0
FLASH POINT

145 C

STABILITY Stable under ordinary conditions

APPLICATIONS

Flavor enhancers and maskers, pH buffers and stabilizers, an ingredient in pharmaceutical products, food and personal care products and as a chemical intermediate.

SALES SPECIFICATION

TECHNICAL GRADE

APPEARANCE

white to off-white crystalline powder

ASSAY (DRY BASIS)

98.5% min

LOSS ON DRYING

0.5% max

CHLORIDE

0.5% max

Fe

0.003% max

FEED GRADE

APPEARANCE

white to off-white crystalline powder

ASSAY (DRY BASIS)

98.5% min

CHLORIDE

0.5% max

HEAVY METALS

20ppm max

ARSENIC

3ppm max

LOSS ON DRYING

0.2% max

FOOD GRADE

BIBLIOGRAPHY

FCC IV

APPEARANCE

white, odorless, crystalline powder

ASSAY (DRY BASIS)

99.0% min

IDENTIFICATION

passes test

LOSS ON DRYING

0.2% max

CHLORIDE

0.002% max

HEAVY METALS

20ppm max

SULPHATE

50ppm max

pH

5.5 - 7.0

RESIDUE ON IGNITION

0.05% max

As

3ppm max

Pb

5ppm max

USP/BP GRADE

BIBLIOGRAPHY

USP 24 / BP 93

APPEARANCE

white, odorless, crystalline powder

ASSAY (DRY BASIS)

99.0 -101.0%

IDENTIFICATION

passes test

LOSS ON DRYING

0.2% max

CHLORIDE

70ppm max

HEAVY METALS

20ppm max

SULPHATE

65 ppm

pH

5.5 - 6.5

RESIDUE ON IGNITION

0.1% max

As

3ppm max

Pb

5ppm max

HYDROLYZABLE SUBSTANCES

passes test

PYROGEN CONTENT

meets the requirements

ALUMINUM

meets the requirements

ORGANIC VOLATILES

meets the requirements

TRANSPORTATION
PACKING
25kgs in Fiber Drum
HAZARD CLASS Not regulated
UN NO.  

GENERAL PROPERTIES OF GLYCINE

Glycine is a white, crystalline amino acid; dissolve in water and. As also known as aminoacetic acid, it is the simplest amino acid. It has acid group as well as amino group which both groups act as a base. It is not optically active, i.e., it does not have d- and l-stereoisomers as two hydrogens are bonded to the central carbon atom. It is nonessential amino acids for mammals; i.e., they can synthesize it from amino acids serine and threonine and from other sources and do not require dietary sources. It is commercially synthesis from ammonia. It is also prepared from bromoethanoic acid by reaction with potassium phthalimide. It helps to improve glycogen storage utilized in the synthesis of hemoglobin, collagen, and glutathione, and facilitates the amelioration of high blood fat and uric acid levels.

GENERAL DESCRIPTION OF AMINO ACID

Amino Acid is any of the organic compounds in which one (or more ) amino group (-NH2) and one (or more ) carboxylic acid group (-COOH) are both present with general formula R-CH(NH2)COOH containing carbon, hydrogen, oxygen, nitrogen, and in certain cases sulfur atoms. Two groups attached to the same carbon (called the alpha-carbon atom at the end of the compound) are polymerized to form peptides and proteins. The amine group is protonated to form -NH3+ at low pH. The carboxylic acid group is deprotonated to form -CO2- at high pH. The carbon atom in the carboxyl group of one amino acid binds covalently to the nitrogen atom in the amino group of another amino acid to form a peptide bond with the release of a water molecule. Proteins are synthesized through the covalent chemical polypeptide bonds. The sequence of these amino acids in the protein polypeptides determines the shape, properties, and hence biological role of the protein that function as chemical messengers and as intermediates in metabolism. Proteins are composed of various proportions of about 20 commonly occurring amino acids. Plants or other biological systems can synthesize amino acids from simple inorganic compounds, but animals rely on adequate supplies in their diet. More than 100 common amino acids occur in plants or in other microorganic systems. The 20 amino acids commonly found in animals are Alanine, Arginine, Asparagine, Aspartic Acid, Cysteine, Glutamic Acid, Glutamine, Glycine, Histidine, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Proline, Serine, Threonine, Tryptophan, Tyrosine, and Valine. Many of the amino acids can be synthesized in the human or animal body from other cellular metabolites when needed (called Non-essential Amino Acids). Animals are not able to synthesize some amino acids necessary in metabolism in sufficient quantities. It must therefore be present in the diet (called Essential Amino Acids). In man, these essential amino acids are Arginine, Histidine, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Threonine, Tryptophan and Valine.

GENERAL PROPERTIES OF AMINO ACIDS

Amino Acid

Abbreviation

Formula (Mol WT)

pK1

pK2

pKR

pI

Hydropathy Index

3-Letters

1-Letter

-COOH

-NH3+

R group

Alanine

Ala

A

C3H7NO2 (89.09)

2.34

9.69

-

6.00

1.8

Arginine

Arg

R

C6H14N4O2(174.20)

2.17

9.04

12.48

10.76

-4.5

Asparagine

Asn

N

C4H8N2O3(132.12)

2.02

8.80

-

5.41

-3.5

Aspartic Acid

Asp

D

C4H7NO4(133.10)

1.88

9.60

3.65

2.77

-3.5

Cysteine

Cys

C

C3H7NO2S(240.30)

1.96

10.128

8.18

5.07

2.5

Glutamic Acid

Glu

E

C5H9NO4(147.13)

2.19

9.67

4.25

3.22

-3.5

Glutamine

Gln

Q

C5H10N2O3(146.15)

2.17

9.13

-

5.65

-3.5

Glycine

Gly

G

C2H5O2(75.07)

2.34

9.60

-

5.97

-0.4

Histidine

His

H

C6H9N3O2(155.16)

1.82

9.17

6.00

7.59

-3.2

Isoleucine

Ile

I

C6H13NO2(131.18)

2.36

9.60

-

6.02

4.5

Leucine

Leu

L

C6H13NO2(131.18)

2.36

9.60

-

5.98

3.8

Lysine

Lys

K

C6H14N2O2(146.19)

2.18

8.95

10.53

9.74

-3.9

Methionine

Met

M

C5H11NO2S(149.21)

2.28

9.21

-

5.74

1.9

Phenylalanine

Phe

F

C9H11NO2(165.19)

1.83

9.13

-

5.48

2.8

Proline

Pro

P

C5H9NO2(115.13)

1.99

10.60

-

6.30

1.6

Serine

Ser

S

C3H7NO3(105.19)

2.21

9.15

-

5.58

-0.8

Threonine

Thr

T

C4H9NO3(119.12)

2.09

9.10

-

5.60

-0.7

Tryptophan

Trp

W

C11H10N2O2(204.23)

2.83

9.39

-

5.89

-0.9

Tyrosine

Tyr

Y

C9H11NO3(181.19)

2.20

9.11

10.07

5.66

-1.3

Valine

Val

V

C5H11NO2(117.15)

2.32

9.62

-

5.96

4.2