CHROMIUM PICOLINATE

PRODUCT IDENTIFICATION
CAS NO. 14639-25-9

CHROMIUM PICOLINATE 

EINECS NO.  
FORMULA Cr(C6H4NO2)3
MOL WT. 418.30

H.S.CODE

 2933.39.6190

TOXICITY

 
SYNONYMS

Chromium tripicolinate; Chromium 2-pyridinecarboxylate;

Chromium picolinate; Chromium(III) trispicolinate; Tris(picolinato)chromium; Divista; Picolinic acid chromium salt; 2-Pyridinecarboxylic acid chromium salt; Tris(2-pyridinecarboxylato-kappaN1,kappaO2)chromium; Cr(pic)3; CrPic;

SMILES [Cr+3].c1(ncccc1)C(=O)[O-].c1(ccccn1)C(=O)[O-].c1(ccccn1) C(=O)[O-]

CLASSIFICATION

 Dietary supplement

EXTRA NOTES

 Chromium complex of tripicolinate; increases glucose uptake by skeletal muscle cultures.
Chromium picolinate is a supplemental or alternative medication for type 2 diabetes and an anti-diabetic mechanisms of CrPic in insulin-resistant 3T3-L1 adipocytes

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

red free-flowing powder

MELTING POINT  
BOILING POINT  
SPECIFIC GRAVITY

 

SOLUBILITY IN WATER Slightly soluble
SOLVENT SOLUBILITY Insoluble in ethanol
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 Health: 1; Flammability: 0; Reactivity: 0

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY

Stable under ordinary conditions. Hygroscopic

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - Chromium picolinate

PubChem Compound Summary - Chromium picolinate

Drug Bank -  Chromium picolinate

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Chromium picolinate

http://www.ebi.ac.uk/chebi/ -  Chromium picolinate

http://www.ncbi.nlm.nih.gov/ -  Chromium picolinate

http://www.efsa.europa.eu/
Zinc picolinate and chromium picolinate are proposed to be used as sources of zinc and chromium, respectively, in food supplements. The majority of studies reveal a slightly greater bioavailability of zinc from zinc picolinate than from other zinc compounds, although some studies showed similar levels of absorption, and a few investigators claim a somewhat lower absorption of zinc from zinc picolinate than from other zinc compounds. Based on studies on chromium intervention, it appears that chromium from chromium picolinate is also equally or slightly better absorbed than chromium from other chromium compounds, although direct studies on the bioavailability are limited and generally bioavailability of inorganic chromium(III) from food sources and food supplements is very low (0.1-2%).

http://www.sigmaaldrich.com/
Chromium picolinate (CrPic) is a supplemental or alternative medication for type 2 diabetes. Experimental evidence shows the effect of CrPic on glucose uptake through the activation of p38 MAPK.1 Chromium is thought to potentiate the action of insulin, leading to increased insulin sensitivity in type 2 diabetes
SALES SPECIFICATION

APPEARANCE

red free-flowing powder

CONTENT

98.0 - 102.0%

Chromium CONTENT

12.3% min

FINENESS

99.0% min (180µm)

LOSS ON DRYING

2.5% max

HEAVY METALS

20ppm max

ARSENIC

5ppm max

CHLORIDE

0.06% max
SULFATE

0.2% max
TRANSPORTATION
PACKING
 
HAZARD CLASS Not regulated
UN NO.  
SAFETY INFORMATION

Hazard Overview

Not known

PRICE INFORMATION