2-CHLORONICOTINIC ACID

PRODUCT IDENTIFICATION

CAS NO. 2942-59-8

2-CHLORONICOTINIC ACID

EINECS NO. 220-937-0
FORMULA C6H4ClNO2
MOL WT. 157.56

H.S. CODE

2933.39

TOXICITY

 
SYNONYMS 2-Chloro-3-pyridinecarboxylic acid; 2-Chloroniacin;
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE off-white to brown powder
MELTING POINT 181 C (Decomposes)
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER Slightly soluble
pH  
VAPOR DENSITY  

AUTOIGNITION

 

NFPA RATINGS

Health: 1 Flammability: 1 Reactivity: 0

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY Stable under ordinary conditions

GENERAL DESCRIPTION AND APPLICATIONS

Niacin (also called Nicotinic Acid) and Niacinamide (also called Nicotinamide), two compounds of water-soluble vitamin B complex, are active in the metabolism of body. Chemically they are 3-Pyridinecarboxylic acid and 3-Pyridinecarboxamide respectively. Commercially, niacin is obtained from beta -picoline or from quinoline, which are both obtainable from coal tar. Niacinamide, more water soluble, is the amide form of niacin. When an amide molecule attaches itself to niacin, it becomes niacinamide. The B vitamins niacin and niacinamide are known as preventives of pellagra. Niacin is interchangeable in metabolism with its amide, niacinamide. Nicotinamide is hydrolyzed to the acid in the digestive tract of non-ruminants. After absorption in the mucosa, the amide is formed again. In the rumen of ruminants, nicotinamide is converted in a short time to nicotinic acid. Nicotinamide and nicotinic acid are therefore equivalent in action in the case of farm animals. These are key ingredients in animal feed and animal feed premixes as these contribute to numerous metabolic reactions  as hydrogen-transferring coenzymes. 2-Chloronicotinic acid is used as an intermediate for agrochemicals, feed additives, pharmaceuticals and animal food enrichments. Niacin acts to reduce plasma cholesterol, as a vasodilator and to treat pellagra.  Niacin is used for the prophylaxis. Their derivatives are used for these effects.

SALES SPECIFICATION

APPEARANCE

off-white to brown powder
ASSAY

97.0 - 101.0%

MOISTURE 0.1% max
TRANSPORTATION
PACKING
25kgs in fiber drum
HAZARD CLASS Not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases:36/37/38, Safety Phrases: 24/25/28A-37-45