MALEIC HYDRAZIDE

PRODUCT IDENTIFICATION
CAS NO. 123-33-1

MALEIC HYDRAZIDE

EINECS NO. 204-619-9
FORMULA C4H4N2O2
MOL WT. 112.09

H.S. CODE

 2933.99.8290

TOXICITY

  
SYNONYMS 3,6-Pyridazinediol; Maleic acid hydrazide; Maleic hydrazide;
1,2-Dihydro-3,6-pyridazinedione; 1,2-Dihydropyridazine-3,6-dione; 3,6-Dihydroxypyridazine; 1,2,3,6-Tetrahydro-3,6-dioxopyridazine; 3,6-Dioxopyridazine; 3,6-Pyridazinediol; 6-Hydroxy-2H-pyridazin-3-one; 6-Hydroxy-3(2H)-pyridazinone; Antergon; Antyrost; Burtolin; Hydrazid kyseliny maleinove; Hydrazide maleique; Maleic acid cyclic hydrazide; Maleic acid hydrazide; Maleic hydrazide; Milurit; N,N-Maleoylhydrazine; Unriprim; Vondalhyde; Vondrax; Other RN: 10071-13-3, 220787-04-2, 48100-18-1, 5425-79-6, 66988-32-7, 92335-53-0
SMILES

[nH]1[nH]c(ccc1=O)=O

CLASSIFICATION

Herbicide, Plant Growth Regulator

EXTRA NOTES

 EPA Pesticide Chemical Code 051501
Overall Carcinogenic Evaluation: Group 3
A herbicide and plant growth regulator; also used to control suckering of tobacco. Its residue in food and tobacco is highly toxic, causing CNS disturbances and liver damage.

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white cystals
MELTING POINT 299 C (Decomposes)
BOILING POINT

 

SPECIFIC GRAVITY

1.6

SOLUBILITY IN WATER slightly soluble (slightly soluble in alcihol)

SOLVENT SOLUBILITY

  
pKa 5.67
VAPOR DENSITY

 

REFRACTIVE INDEX

  
AUTOIGNITION

 

NFPA RATINGS Health: 2; Flammability: 0; Reactivity: 0
FLASH POINT

 

STABILITY Stable under ordinary conditions. Light & moisture sensitive

GENERAL DESCRIPTION & APPLICATIONS
Hydrazide is an acyl hydrazine. Acyl (-CO) is an organic radical formed by removal of a hydroxyl group from an organic acid (carboxyl group). Maleic Hydrazide is a compound belongs to the class of pyridazinediones, 6-membered aromatic rings containing two adjacent nitrogen atoms (pyridazine), doubly substituted with oxygen. Pyridazinedione structure binds to amino acids to behave biologically in the body and acts as the inhibitory GABA (gamma-aminobutyric acid) receptor in brain. It is studied in medicinal chemistry. Maleic Hydrazide is used in horticulture and agriculture field as a weed killer and growth inhibitor (nonauxin plant regulator). It is used as a chemical intermediate for the synthesis of other pyridazine and dione compounds.
SALES SPECIFICATION

APPEARANCE

 white crystal

PURITY

99.0% min

LOSS ON DRYING

1.0 % max

ASH

0.1% max

pH

2.0 ~ 4.0
TRANSPORTATION
PACKING

 

HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38 , Safety Phrases: 24/25

GENERAL DESCRIPTION OF AUXIN
Auxin is one of five (or more) major plant hormones (Auxin, Cytokinins, Gibberellins, Ethylene and Abscisic acid) which affect numerous plant growth processes functions including cell division and elongation, autumnal loss of leaves, and the formation of buds, roots, flowers, and fruit. Auxin action is inhibited by light which is an important role of the growth of stems toward light (phototropism), against the force of gravity (geotropism) and positively hydrotropic (moisture-seeking). The cells exposed to light don't grow as quickly as those on the shaded side, and thus the plant grows toward the light source. Auxins usually have a ring system with at least one double bond and attached by a side-chain that terminates in a carboxyl group. Indole acetic acid is the exact structure of Auxin activity. Parent compounds of auxin action are;
  • Auxins
    • 4-Chlorophenoxyacetic acid (CAS RN: 122-88-3)
    • (2,4-Dichlorophenoxy)acetic acid (CAS RN: 94-75-7)
    • 4-(2,4-Dichlorophenoxy)butyric acid (CAS RN: 94-82-6)
    • Tris[2-(2,4-Dichlorophenoxy)ethyl] phosphite (CAS RN: 94-84-8)
    • 2-(2,4-Dichlorophenoxy)propanoic acid (CAS RN: 120-36-5)
    • 2-(2,4,5-trichlorophenoxy)propanoic acid (CAS RN: 93-72-1)
    • Indole-3-acetic acid (CAS RN: 87-51-4)
    • Indole-3-butyric acid (CAS RN: 133-32-4)
    • 1-Naphthaleneacetamide (CAS RN: 86-86-2)
    • 1-Naphthaleneacetic acid (CAS RN: 86-87-3)
    • 1-Naphthol (CAS RN: 90-15-3)
    • Naphthoxy acetic acid (CAS RN: 120-23-0)
    • Naphthenic acid, inorganic salts (potassium, sodium)
    • (2,4,5-Trichlorophenoxy) Acetic acid (CAS RN: 93-76-5)
  • Antiauxins
    • Clofibric acid (CAS RN: 882-09-7)
    • 2,3,5-Triiodobenzoic acid (CAS RN: 88-82-4)

Cytokinin is a N6-substituted adenines acting as phytohormones  such as kinetin, zeatin, 6-isopentenyladenine, benzyl adenine. The principal functions are stimulate cell division in concert with auxin (cytokinesis) and influence the pathway of tissue differentiation (organogenesis). 6-Benzylaminopurine is the first generation synthetic cytokinin which elicits plant growth and development responses setting blossoms and stimulating fruit richness by stimulating cell division. Active cytokinin ingredients include:

  • Adenine (CAS RN: 73-24-5)
  • Adenine Hemisulfate salt (CAS RN: 321-30-2)
  • 6-Benzylaminopurine (CAS RN: 1214-39-7(base), 162714-86-5(HCl)
  • N-Benzyl-9-(2-tetrahydropyranyl)adenine (CAS RN: 2312-73-4)
  • N-(2-Chloro-4-pyridyl)-N'-phenylurea (CAS RN: 68157-60-8)
  • 6-(gamma,gamma-Dimethylallylamino)purine (CAS RN: 2365-40-4)
  • 1,3-Diphenylurea (CAS RN: 102-07-8)
  • Kinetin (CAS RN: 525-79-1 (base), 177966-68-6 (HCl)
  • 1-Phenyl-3-(1,2,3-thiadiazol-5-yl) Urea (CAS RN: 51707-55-2)
  • Zeatin (CAS RN: 13114-27-7)
  • trans-Zeatin (CAS RN: 1637-39-4 (base), 6025-81-6 (HCl))
  • trans-Zeatin riboside (CAS RN: 6025-53-2)

Other Plant Growth Regulators include:

  • Abscisic acid (CAS RN: 21293-29-8)
  • Ancymidol (CAS RN: 12771-68-5)
  • Chlorocholine chloride (CAS RN: 999-81-5)
  • Daminozide (CAS RN: 1596-84-5)
  • 3,6-Dichloro-o-anisic acid (CAS RN: 1918-00-9)
  • Gibberellic acid (CAS RN: 77-06-5)
  • Gibberellic acid Potassium salt (CAS RN: 125-67-7)
  • Gibberellin A4 (CAS RN: 468-44-0  ) and other gibberellins (more than 110 gibberellins are known)
  • Glyphosate (CAS RN: 1071-83-6)
  • Jasmonic acid (CAS RN: 3572-66-5)
  • 1,3,5-Trihydroxybenzene (CAS RN: 108-73-6)