BENZYL CHLOROFORMATE

PRODUCT IDENTIFICATION
CAS NO. 501-53-1

BENZYL CHLOROFORMATE

EINECS NO. 207-925-0
FORMULA ClCO2CH2C6H5
MOL WT. 170.60

H.S. CODE

 2915.90.2000

TOXICITY

 Oral rat LD50: 3gr/kg
SYNONYMS Cbz chloride; ; Carbonochloridic acid phenylmethyl ester;
Carbobenzloxy chloride; Chloroformic acid benzyl ester; Benzylcarbonyl chloride; Benzyl chlorocarbonate; Benzylcarbonyl chloride; Benzyloxycarbonyl chloride; Carbobenzyloxy chloride; Chloroformic acid benzyl ester; BCF; BZCF; Benzyl chloroformate; Other RN: 728010-31-9, 94274-21-2
SMILES

c1(COC(=O)Cl)ccccc1

CLASSIFICATION

 

EXTRA NOTES

  

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE clear to yellow liquid, phosgene odor
MELTING POINT 0 C
BOILING POINT 152 C (Decomposes)
SPECIFIC GRAVITY 1.195 - 1.22
SOLUBILITY IN WATER Insoluble
pH  
VAPOR DENSITY 1.0

REFRACTIVE INDEX

  
AUTOIGNITION

 

NFPA RATINGS Health: 3; Flammability: 1; Reactivity: 0
FLASH POINT 105 C
STABILITY

Stable under ordinary conditions, moisture sensitive

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - Benzyl Chloroformate

PubChem Compound Summary - Benzyl Chloroformate

http://www.ebi.ac.uk/ -  Benzyl Chloroformate

http://www.ncbi.nlm.nih.gov/ -  Benzyl Chloroformate

Material Safety Data Sheet

Local:
Phosgene (carbonyl dichloride, COCl2) is a very reactive chemical intermediate to prepare isocyanates, chloroformates, isothiocyanates, isonitriles and acid chlorides as well as in the production of polymers including polyurethanes, polycarbonates, and polyureas. Phosgene , however, is extremely toxic gas associated strong safety hazards and handling precautions. It is listed on schedule 3 of the Chemical Weapons Convention. All production sites must be declared to the OPCW. Phosgene is almost entirely in captive consume in the production plant. Chloroformates are relatively less dangerous route to prepare important families of compounds, the carbonates and carbamates. Carbonates are prepared by reaction with alcohol (or phenol) and carbamates are by reaction with an amine ( primary or secondary). Chloroformates are starting materials to prepare carbonate and carbamate derivatives that are used in the pharmaceutical and agrochemical industry.

Benzyl chloroformate is used as an intermediate for the synthesis of pharmaceuticals and agrochemicals especially for some carbamates (salt or ester of an amide of carbonic acid) which are used as insecticides, fungicides, herbicides, sprout inhibitors and biocides. Peptide grade is used to block the amino group in peptide synthesis.
SALES SPECIFICATION

TECH GRADE

APPEARANCE

 clear to yellow liquid

ASSAY

98.0% min

PHOSGENE

0.5% max

IRON

2ppm max

FREE Cl

0.5% max
TRANSPORTATION
PACKING

 

HAZARD CLASS 8 (Packing Group:I)
UN NO.

1739

SAFETY INFORMATION

HAZARD OVERVIEW

Combustible Liquid, Target Organ Effect, Highly toxic by inhalation, Harmful by ingestion., Corrosive, Carcinogen. Target Organs: Kidney, Liver, Blood

GHS

 
SIGNAL WORD Danger

PICTOGRAMS

HAZARD STATEMENTS

H314-H335-H350-H410

P STATEMENTS

P201-P261-P273-P280-P305 + P351 + P338-P310
EC DIRECTIVES

 
HAZARD CODES

RISK PHRASES

45-34-37-50/53

SAFETY PHRASES

53-26-36/37/39-45-61
PRICE INFORMATION