2-PHENYLPHENOL

PRODUCT IDENTIFICATION

CAS NO. 90-43-7, 39387-78-5, 192076-92-9

2-PHENYLPHENOL

EINECS NO. 201-993-5
FORMULA C6H5C6H4OH
MOL WT. 170.21

H.S. CODE

2907.19.8000

TOXICITY

Oral rat LD50; 2000 mg/kg
SYNONYMS o-Phenylphenol; 1,1'-Biphenyl-2-ol; (1,1-Biphenyl)-2-ol;
Hydroxy-2-phenylbenzene; Hydroxdiphenyl; Hydroxybiphenyl; Biphenylol; Biphenyl-2-ol; Xenol; 2-Hydroxybiphenyl; Orthoxenol; 2-Biphenylol; o-Xonal; o-Hydroxydipbenyl; 2-Phenylphenol; Dowicide A; 1-Hydroxy-2-phenylbenzene; 2-Biphenylol; 2-Fenylfenol; Orthohydroxydiphenyl; Orthophenylphenol; o-Hydroxybiphenyl;
SMILES

c1(c2c(cccc2)O)ccccc1

CLASSIFICATION

Disinfectants, Fungicide, Bactericide, Preservative; Germicide, bactericide, Anti-infective agent, Antiseptic, Biphenyl

EXTRA NOTES

Overall Carcinogenic Evaluation: Group 3

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white flakes, mild odor
MELTING POINT 56 - 59 C
BOILING POINT

282 C

SPECIFIC GRAVITY

1.293

SOLUBILITY IN WATER Very slightly soluble (0.7 g/l at 25 C)

SOLVENT SOLUBILITY

Soluble in alcohol, NaOH solution
VAPOR DENSITY

 

pKa 9.97 (Dissociation Constant at 25 C)
log P 3.09 (Octanol-water)
HENRY LAW CONSTANT 1.05E-06 (atm-m3/mole at 25 C)
OH RATE CONSTANT 2.73E-11 (cm3/molecule-sec at 25 C Atmospheric)

REFRACTIVE INDEX

 
AUTOIGNITION

530 C

NFPA RATINGS Health: 3; Flammability: 1; Reactivity: 0
FLASH POINT

123 C

STABILITY

Stable under ordinary conditions

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Material Safety Data Sheet

Google Scholar Search

http://www.dormer.ca/
What is 2-Phenylphenol and where is it found: This chemical is used in the manufacture of dyes and resins, rubber chemicals, fungicides, germicides, preservatives and food packaging. It is used as a disinfectant and fungicide for impregnation of fruit wrappers and seed boxes. It can also be found in household disinfectants, some cosmetics, cooling fluids and detergents. Further research may identify additional product or industrial usages of this chemical.

http://www.bvsde.ops-oms.org/
2-Phenylphenol (CAS No. 90-43-7) is used as a disinfectant, bactericide and virucide. In agriculture, it is used in disinfecting fruits, vegetables and eggs. It is also used as a general surface disinfectant in hospitals, nursing homes, veterinary hospitals, poultry farms, dairy farms, commercial laundries, barbershops and food processing plants. 2-Phenylphenol is readily degraded in surface waters, with a half-life of about 1 week in river water. 2-Phenylphenol has been determined to be of low toxicity. Both 2-phenylphenol and its sodium salt are carcinogenic in male rats, and 2-phenylphenol is carcinogenic in male mice. However, urinary bladder tumours observed in male rats and liver tumours observed in male mice exposed to 2-phenylphenol appear to be threshold phenomena that are species- and sex-specific. JMPR has concluded that 2-phenylphenol is unlikely to represent a carcinogenic risk to humans. Although a working group convened by IARC has classified 2-phenylphenol, sodium salt, in Group 2B (possibly carcinogenic to humans) and 2-phenylphenol in Group 3 (not classifiable as to its carcinogenicity to humans), JMPR noted that the IARC classification is based on hazard identification, not risk assessment, and is furthermore limited to published literature, excluding unpublished studies on toxicity and carcinogenicity. JMPR also concluded that there are unresolved questions about the genotoxic potential of 2-phenylphenol.

Local:  Phenylphenol is used in formulating biocides and preservatives. It can be used as a additive for food packaging materials, seed boxes and household goods as a disinfectant and fungicide. Phenylphenol is used to manufacture germicide, fungicide, rubber chemicals and dyes.

GENERAL DESCRIPTION OF BIPHENYL: Biphenyl (also called Diphenyl, but exactly one of two compounds. The other is o-phenylphenol, used to prevent the growth of moulds ) is an aromatic hydrocarbon; molecule structure is composed of two six-sided carbon rings connected at one carbon site on each ring. Pure biphenyl is a toxic colourless crystalline solid with a pleasant odour; melting point 70 C, boiling point 255 C, which gives plates or monoclinic prismatic crystals; it is insoluble in water but soluble in ordinary organic solvents. It is directly used in the preservation of citrus fruits  as a fungistat in transportation containers. It is a raw material for polychlorinated diphenyls (PCB) in which chlorine replaces hydrogen in biphenyls. There are 209 chlorinated isomers of biphenyl theoretically. But PCBs are referred to the biphenyl compounds with one to ten chlorine substitutions. PCBs are used heat-transfer agents and as electric insulators that block the flow of electric current across in electrical equipments. They are known as environmental pollution materials which are accumulated in animal tissues and cause toxic effects including carcinogenesis. Biphenyl is used as an intermediate for the production of a wide range of organic compounds (e.g. emulsifiers, optical brighteners, crop protection products, plastics), as a heat transfer medium alone or with diphenyl ether in heating fluids, as a dyestuff carrier for textiles and copying paper and as a solvent in pharmaceutical production. Aminodiphenyls are used as rubber antioxidants and intermediates for the synthesis of organic compounds ( azo dyes and pharmaceuticals). Biphenyl derivatives are used as an intermediate for the synthesis of organic compounds including pharmaceuticals, antifungal agents, optical brightening agents and dyes. Biphenyl compounds also used in luminescence chemistry, spectrophotometric analysis, molecular chemistry, and as a stating material for organometallic-complexes.

SALES SPECIFICATION

APPEARANCE

white flakes

ASSAY

99.0% min

MELTING POINT 56 - 59 C

MOISTURE

0.1% max

TRANSPORTATION
PACKING

 

HAZARD CLASS 9 (Packing Group: III)
UN NO. 3077
SAFETY INFORMATION

GHS

 

SIGNAL WORD Warning

PICTOGRAMS

HAZARD STATEMENTS

H315:  Causes skin irritation
H335:  May cause respiratory irritation
H319:  Causes serious eye irritation\
H400:  Very toxic to aquatic life

PRECAUTIONARY STATEMENTS

P304 + P340:  IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
P261:  Avoid breathing dust/fume/gas/mist/vapors/spray
P273:  Avoid release to the environment
P302+ P352:  IF ON SKIN: Wash with plenty of soap and water
P280:  Wear protective gloves/protective clothing/eye protection/face protection
P305 + P351 + P338:  IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

EC DIRECTIVES

 

HAZARD CODES

Xi IrritantN Dangerous for the environment

RISK PHRASES

36/37/38:  Irritating to eyes, respiratory system and skin.
50:  Very toxic to aquatic organisms.

SAFETY PHRASES

22:  Do not breathe dust.
61:  Avoid release to the environment. Refer to special instructions / safety data sheets.

PRICE INFORMATION