1-BROMOPROPANE

PRODUCT IDENTIFICATION

CAS NO

106-94-5

1-BROMOPROPANE

EINECS NO.

203-445-0

FORMULA CH3CH2CH2Br
MOL WT. 122.99
H.S. CODE 2903.39.1550

TOXICITY

Oral rat LD50: 4260 mg/kg

SYNONYMS

n-Propyl Bromide; Bromure n-propylène (French); 1-Bromopropane;

n-Propilbromuro (Spanish); Propane, 1-Bromo-; 溴代正丙烷 (Chinese); Propyl bromide;

SMILES

C(CBr)C

CLASSIFICATION

Solvent

EXTRA NOTES

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE Clear to slightly yellow liquid
MELTING POINT -110 C
BOILING POINT 71 C
SPECIFIC GRAVITY 1.353
SOLUBILITY IN WATER 0.25g / 100ml
SOLVENT SOLUBILITY Soluble in alcohol, acetone. ether
pH

6 - 8

VAPOR DENSITY 4.25
AUTOIGNITION

 

log P 2.1 (Octanol-water)
VAPOR PRESSURE 111 (mmHg)
HENRY LAW CONSTANT 7.32E-03 (atm-m3/mole at 25 C)
OH RATE CONSTANT 1.18E-12 (cm3/molecule-sec at 25 C Atmospheric)
NFPA RATINGS Health: 2 Flammability: 3 Reactivity: 0

REFRACTIVE INDEX

1.4343
FLASH POINT

25 C

STABILITY Stable under ordinary conditions

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Material Safety Data Sheet

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - 1-BROMOPROPANE

PubChem Compound Summary - 1-BROMOPROPANE

http://www.cdc.gov/
1-Bromopropane (1-BP) (n-propyl bromide) is a solvent increasingly used as a substitute for ozone-depleting chloro-fluorocarbons and similar regulated compounds. 1-BP is used in vapor and immersion degreasing operations and other manufacturing processes, and as a solvent in industries using aerosol-applied adhesives. In some states, 1-BP is used as a solvent in dry cleaning because of restrictions on use of perchloroethylene (tetrachloroethylene), a possible human carcinogen (
1). Published studies of workers exposed to 1-BP have raised concerns about occupational health risks associated with exposure (2--5). This report describes two cases involving workers exposed to 1-BP and diagnosed with clinical manifestations of neurotoxicity. The cases, when coupled with previously reported studies of workers exposed to 1-BP, illustrate potential health risks of 1-BP exposure. Clinicians and public health professionals should be alert to potential health effects among workers exposed to 1-BP, particularly in dry cleaning and other workplaces where 1-BP use might be increasing, and effective control methods to limit exposure to 1-BP should be implemented at worksites.

Local:
1-Bromopropane, also known as n-propyl bromide is a primary alkyl halide, with the formula CH3CH2CH2Br . 2-Bromopropane has bromine atom at the second position, also called isopropyl bromide. The formula is CH3CHBrCH3. They are bromine atom position isomers. They are colorless liquid, insoluble in water, but soluble in ethanol and ether. They are used as alkylating agents to introduce the alkyl groups to form carbon-carbon bonds in organic synthesis. They are also used as  intermediate to form alkylated amines and alkylated metallic compounds. The end products include pharmaceuticals, insecticides, quaternary ammonium compounds, flavours and fragrances.

They are also used as solvent for industrial cleaning (degreasing, metal processing and finishing, electronics, aerospace and aviation), aerosols, textiles, adhesives , inks and coatings.

SALES SPECIFICATION

APPEARANCE

Clear to slightly yellow liquid

ASSAY

99.0% max

FREE HBr

0.01% max

WATER

0.05% max

COLOR (APHA)

50 max

TRANSPORTATION
PACKING 250kgs in Drum
HAZARD CLASS 3.2 (Packing group II)
UN NO. 2344
SAFETY INFORMATION

HAZARD OVERVIEW

OSHA Hazards:Flammable liquid, Irritant, Teratogen, Reproductive hazard

GHS

 

SIGNAL WORD

Danger

PICTOGRAMS

HAZARD STATEMENTS

H225 Highly flammable liquid and vapour.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 + H336 May cause respiratory irritation, and drowsiness or dizziness.
H360 May damage fertility or the unborn child.
H371 May cause damage to organs.
H412 Harmful to aquatic life with long lasting effects.

PRECAUTIONARY STATEMENTS

P201 Obtain special instructions before use.
P210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P273 Avoid release to the environment.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.

EC DIRECTIVES

 

HAZARD CODES

F Highly FlammableT Toxic

RISK PHRASES

11 Highly Flammable
36/37/38  
Irritating to eyes, respiratory system and skin
48/20  Harmful: danger of serious damage to health by prolonged exposure through inhalation
60  May impair fertility
63  Possible risk of harm to the unborn child
67
Vapors may cause drowsiness and dizziness

SAFETY PHRASES

45  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
53  Avoid exposure - obtain special instruction before use

PRICE INFORMATION