AZELAIC ACID

PRODUCT IDENTIFICATION

CAS NO. 123-99-9

AZELAIC ACID

EINECS NO. 204-669-1
FORMULA HOOC(CH2)7COOH
MOL WT. 188.22
H.S. CODE

2917.19

TOXICITY

 
SYNONYMS 1,9-Nonanedioic acid; n-Nonanedioic acid;
Anchoic acid; Lepargylic acid; 1,7-Heptanedicarboxylic acid; Heptanedicarboxylic acid; Azelainic acid; 1,7-Dicarboxyheptane;

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white crystals
MELTING POINT 98 - 102 C
BOILING POINT

286 C at 100 mmHg

SPECIFIC GRAVITY  
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY  

AUTOIGNITION

 

NFPA RATINGS

Health: 1; Flammability: 0; Reactivity: 0

REFRACTIVE INDEX

 
FLASH POINT

210 C

STABILITY Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS

Azelaic Acid, dicarboxylic acid with 9 carbon atoms, is a white flake or powdered crystal. It is resolved in ethanol, ether and soluble slightly in water. Azelaic Acid can be prepared by ozonolysis which uses ozone is to cleave the alkene bonds. Example of ozonolysis in commerce is the production of odd carbon number carboxylic acids such as azelaic acid and pelargonic acid and simple carboxylic acids such as formic acid and oxalic acid. Odd chain number carboxylic acids are relatively high cost material. Azelaic acid is produced naturally on normal skin by a yeast called Malassezia furfur. Azelaic acid is used as a dermatologic agent to treat acnes. Azelaic acid is also known as a 5-alpha reductase inhibitor which is applicable to prevent hair loss. Dicarboxylic acid can yield two kinds of salts, as they contain two carboxyl groups in its molecules. Azelaic Acid and its derivatives have a variety of industrial uses as plasticizers, lubricants, hydraulic fluids, cosmetics, candles, etc. It is used in the synthesis of polyamide and alkyd resins.  It is also used as an intermediate for aromatics, antiseptics and painting materials. Examples of azelate compounds include:

SALES SPECIFICATION

APPEARANCE

white flake
ASSAY

97.0% min

MELTING POINT 105 -107 C
TRANSPORTATION
PACKING  
HAZARD CLASS Not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38 , Safety Phrases: 26-36
GENERAL DESCRIPTION OF DICARBOXYLIC ACID
Dicarboxylic acid is a compound containing two carboxylic acid, -COOH, groups. Straight chain examples are shown in table. The general formula is HOOC(CH2)nCOOH, where oxalic acid's n is 0, n=1 for malonic acid, n=2 for succinic acid, n=3 for glutaric acid, and etc. In substitutive nomenclature, their names are formed by adding -dioic' as a suffix to the name of the parent compound. They can yield two kinds of salts, as they contain two carboxyl groups in its molecules. The range of carbon chain lengths is from 2, but the longer than C 24 is very rare. The term long chain refers to C 12 up to C 24 commonly. Carboxylic acids have industrial application directly or indirectly through acid halides, esters, salts, and anhydride forms, polymerization, and etc. Dicarboxylic acids can yield two kinds of salts or esters, as they contain two carboxyl groups in one molecule. It is useful in a variety of industrial applications include;
  • Plasticizer for polymers
  • Biodegradable solvents and lubricants
  • Engineering plastics
  • Epoxy curing agent
  • Adhesive and powder coating
  • Corrosion inhibitor
  • Perfumery and pharmaceutical
  • Electrolyte

There are almost infinite esters obtained from carboxylic acids. Esters are formed by removal of water from an acid and an alcohol. Carboxylic acid esters are used as in a variety of direct and indirect applications. Lower chain esters are used as flavouring base materials, plasticizers, solvent carriers and coupling agents. Higher chain compounds are used as components in metalworking fluids, surfactants, lubricants, detergents, oiling agents, emulsifiers, wetting agents textile treatments and emollients, They are also used as intermediates for the manufacture of a variety of target compounds. The almost infinite esters provide a wide range of viscosity, specific gravity, vapor pressure, boiling point, and other physical and chemical properties for the proper application selections.

C length (Straight)

Product

CAS #

Melting Point

Boiling Point

C 2

Oxalic Acid
(
Ethanedioic Acid)
144-62-7

189 - 191 C

Sublimes

C 3

Malonic Acid
(
Propanedioic Acid)

141-82-2 131 - 135 C

Decomposes

C 4

Succinic Acid
(Butanedioic Acid)

110-15-6

185 - 190 C

235 C

C 5

Glutaric Acid
(
Pentanedioic Acid)

110-94-1

95 - 99 C

302 C

C 6

Adipic Acid
(Hexanedioic Acid)

124-04-9

151 - 153 C

265 C at 100 mmHg

C 7

Pimelic Acid
(Heptanedioic Acid)

111-16-0

105 - 106 C

212 C at 10 mmHg

C 8

Suberic Acid
(Octanedioic Acid)

505-48-6

143 - 144 C

230 C at 15 mmHg

C 9

Azelaic Acid
(Nonanedioic Acid)

123-99-9

100 - 103 C

237 C at 15 mmHg

C 10

Sebacic Acid
(Decanedioic Acid)

111-20-6

131 - 134 C

294 at 100 mmHg

C 11

Undecanedioic acid 1852-04-6

109 - 110 C

 

C 12

Dodecanedioic acid 693-23-2

128 - 129 C

245 C at 10 mmHg

C 13

Brassylic acid
(
Tridecanedioic acid)
505-52-2

112 - 114 C

 

C 14

Tetradecanedioic acid 821-38-5

126 - 128 C

 

C 15

Pentadecanedioic acid 1460-18-0

 

 

C 16

Thapsic acid
(
Hexadecanedioic acid)
505-54-4

124 - 126 C

 

C 18

Octadecanedioic acid

871-70-5

 

 

PRICE INFORMATION

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