ADIPIC ACID

PRODUCT IDENTIFICATION

CAS NO. 124-04-9

ADIPIC ACID

EINECS NO. 204-673-3
FORMULA

HOOC(CH2)4COOH

MOL WT. 146.142
H.S. CODE 2917.12

TOXICITY

Oral rat LD50: >11 gm/kg
SYNONYMS 1,4-Butanedicarboxylic acid; 1,6-Hexanedioic Acid;
Adipinic Acid; Acifloctin; Acinetten; Hexanedioic acid;

SMILES

C(CCCCC(O)=O)(O)=O

CLASSIFICATION

Dicarboxylic acid, Food acidity regulator

EXTRA NOTES

FEMA No. 2011
Other RN: 1186514-28-2, 7486-39-7 (magnesium salt), 22322-28-7 (calcium salt), 23311-84-4 (hydrochloride salt), 25666-61-9 (potassium salt), 3385-41-9 (ammonium salt), 7486-38-6 (dihydrochloride salt)

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white crystals
MELTING POINT 152 - 154 C
BOILING POINT

337 C

SPECIFIC GRAVITY 1.36
SOLUBILITY IN WATER Slightly soluble
pH

3.45 (1%)

VAPOR DENSITY 5

AUTOIGNITION

420 C

REFRACTIVE INDEX

 

NFPA RATINGS

Health: 1; Flammability: 1; Reactivity: 0
FLASH POINT

210 C

STABILITY Stable under ordinary conditions

GENERAL DESCRIPTION & APPLICATIONS

USA.gov - Adipic Acid

Wikipedia Linking - Adipic Acid

Google Scholar Search - Adipic Acid

U.S. National Library of Medicine - Adipic Acid

PubChem Compound Summary - Adipic Acid

IPCS INCHEM -  Adipic Acid

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Adipic Acid

ChEBI (http://www.ebi.ac.uk/chebi/) -  Adipic Acid

NCBI (http://www.ncbi.nlm.nih.gov/) -  Adipic Acid

Material Safety Data Sheet - Adipic Acid

Human Metabolome Database - Adipic Acid
Adipic acid is an important inudstrial dicarboxylic acid with about 2.5 billion kilograms produced per year. It is used mainly in the production of nylon. It occurs relatively rarely in nature. It has a tart taste and is also used as an additive and gelling agent in jello or gelatins. It is also used in some calcium carbonate antacids to make them tart. Adipic acid has also been incorporated into controlled-release formulation matrix tablets to obtain pH-independent release for both weakly basic and weakly acidic drugs.

Hazardous Substances Data Bank - Adipic Acid

EPA - Substance Registry Services - Adipic Acid

Local:
Adipic Acid (also called hexanedioic acid) is a white, crystalline compound of  C6 straight-chain dicarboxylic acid; slightly soluble in water and soluble in alcohol and acetone. Almost all of the commercial adipic acid is produced from cyclohexane through two sequent oxidation processes. The first oxidation is the reacting of cyclohexane with oxygen in the presents of cobalt or manganese catalysts at a temperature of 150 - 160 C, which produce cyclohexanol and cyclohexanone. Then, the intermediates are further reacted with nitric acid and air with a catalyst (copper or vanadium) or without nitric acid. Cyclohexane can be prepared by the hydrogenation of benzene. There are other ways such as the reactions using phenol, butadiene, and various fats as the starting material. Adipic acid consumption is linked almost 90% to nylon production by the polycondensation with hexamethylenediamine. Nylon, having a protein-like structure, is further processed into fibers for applications in carpeting, automobile tire cord  and clothing. Adipic acid is used in manufacturing plasticizers and lubricants components. It is used in making polyester polyols for polyurethane systems. Food grade adipic acid is used as gelling aid, acidulant, leavening and buffering agent. Adipic acid has two carboxylic acid, -COOH, groups, which can yield two kinds of salts. Its derivatives, acyl halides, anhydrides, esters, amides and nitriles, are used in making target products such as flavoring agents, internal plasticizers, pesticides, dyes, textile treatment agents, fungicides, and pharmaceuticals through further reactions of substitution, catalytic reduction, metal hydride reduction, diborane reduction, keto formation with organometallic reagents, electrophile bonding at oxygen, and condensation.

SALES SPECIFICATION

APPEARANCE

white crystalline powder
CONTENT

99.5% min

COLOR. APHA

5 max

IRON

0.2 ppm max

ASH

7 ppm max

NITRATE

5 ppm max

WATER

0.2% max

TRANSPORTATION
PACKING 25kgs in bag
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36, Safety Phrases:
GENERAL DESCRIPTION OF DICARBOXYLIC ACID
Dicarboxylic acid is a compound containing two carboxylic acid, -COOH, groups. Straight chain examples are shown in table. The general formula is HOOC(CH2)nCOOH, where oxalic acid's n is 0, n=1 for malonic acid, n=2 for succinic acid, n=3 for glutaric acid, and etc. In substitutive nomenclature, their names are formed by adding -dioic' as a suffix to the name of the parent compound. They can yield two kinds of salts, as they contain two carboxyl groups in its molecules. The range of carbon chain lengths is from 2, but the longer than C 24 is very rare. The term long chain refers to C 12 up to C 24 commonly. Carboxylic acids have industrial application directly or indirectly through acid halides, esters, salts, and anhydride forms, polymerization, and etc. Dicarboxylic acids can yield two kinds of salts or esters, as they contain two carboxyl groups in one molecule. It is useful in a variety of industrial applications include;
  • Plasticizer for polymers
  • Biodegradable solvents and lubricants
  • Engineering plastics
  • Epoxy curing agent
  • Adhesive and powder coating
  • Corrosion inhibitor
  • Perfumery and pharmaceutical
  • Electrolyte

There are almost infinite esters obtained from carboxylic acids. Esters are formed by removal of water from an acid and an alcohol. Carboxylic acid esters are used as in a variety of direct and indirect applications. Lower chain esters are used as flavouring base materials, plasticizers, solvent carriers and coupling agents. Higher chain compounds are used as components in metalworking fluids, surfactants, lubricants, detergents, oiling agents, emulsifiers, wetting agents textile treatments and emollients, They are also used as intermediates for the manufacture of a variety of target compounds. The almost infinite esters provide a wide range of viscosity, specific gravity, vapor pressure, boiling point, and other physical and chemical properties for the proper application selections.

C length (Straight)

Product

CAS #

Melting Point

Boiling Point

C 2

Oxalic Acid
(
Ethanedioic Acid)
144-62-7

189 - 191 C

Sublimes

C 3

Malonic Acid
(
Propanedioic Acid)

141-82-2 131 - 135 C

Decomposes

C 4

Succinic Acid
(Butanedioic Acid)

110-15-6

185 - 190 C

235 C

C 5

Glutaric Acid
(
Pentanedioic Acid)

110-94-1

95 - 99 C

302 C

C 6

Adipic Acid
(Hexanedioic Acid)

124-04-9

151 - 153 C

265 C at 100 mmHg

C 7

Pimelic Acid
(Heptanedioic Acid)

111-16-0

105 - 106 C

212 C at 10 mmHg

C 8

Suberic Acid
(Octanedioic Acid)

505-48-6

143 - 144 C

230 C at 15 mmHg

C 9

Azelaic Acid
(Nonanedioic Acid)

123-99-9

100 - 103 C

237 C at 15 mmHg

C 10

Sebacic Acid
(Decanedioic Acid)

111-20-6

131 - 134 C

294 at 100 mmHg

C 11

Undecanedioic acid 1852-04-6

109 - 110 C

 

C 12

Dodecanedioic acid 693-23-2

128 - 129 C

245 C at 10 mmHg

C 13

Brassylic acid
(
Tridecanedioic acid)
505-52-2

112 - 114 C

 

C 14

Tetradecanedioic acid 821-38-5

126 - 128 C

 

C 15

Pentadecanedioic acid 1460-18-0

 

 

C 16

Thapsic acid
(
Hexadecanedioic acid)
505-54-4

124 - 126 C

 

C 18

Octadecanedioic acid

871-70-5

 

 

 

PRICE INFORMATION