PRAZIQUANTEL

Synonyms. Praziquantel; 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one; Biltricide; Droncit; Praziquantelum; Pyquiton;

PRAZIQUANTEL

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

55268-74-1

EINECS RN

259-559-6

FORMULA

C19H24N2O2

MOLE WEIGHT

312.41

H.S CODE

2933.99.7900

SMILES

c12[C@@H]3N(C(CN(C3)C(C3CCCCC3)=O)=O)CCc1cccc2

CLASSIFICATION

Anthelmintic, Anti-Infective, Antiparasitic, Lactam

EXTRA NOTES

An anthelmintic used in most schistosome and many cestode infestations.[MeSH]

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

white crystalline powder

MELTING POINT

136 ~ 140 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

400 mg/l

SOLVENT SOLUBILITY

 

VAPOR DENSITY

 

log P(octanol-water)

2.42

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 1, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Praziquantel

Wikipedia Linking - Praziquantel

Google Scholar Search - Praziquantel

U.S. National Library of Medicine - Praziquantel

PubChem Compound Summary - Praziquantel

Drug Bank -  Praziquantel

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Praziquantel

http://www.ebi.ac.uk/ChEMBL -  Praziquantel

http://www.ncbi.nlm.nih.gov/ -  Praziquantel

EPA - Substance Registry Services - Praziquantel

 

SALES SPECIFICATION

APPEARANCE

white crystalline powder

ASSAY

98.5% ~ 101.0%

MELTING POINT

136 ~ 140 C

RESIDUE ON IGNITION

0.2% max

LOSS ON DRYING

0.5% max

PHOSPHATE

0.05% max

RELATED SUBSTANCES

0.5% max (total), 0.2% max (individual)

SOLVENT RESIDUES

Ethanol 5000ppm max, Chloroform 60 ppm max

HEAVY METALS

10ppm max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

 

HAZARD CLASS

 

PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

GHS (Globally Harmonised System) Classification: Not a dangerous substance. Potential Health Effects: Eyes - May cause eye irritation. Skin - May be harmful if absorbed through skin May cause skin irritation. Inhalation - May be harmful if inhaled. May cause respiratory tract irritation. Ingestion - May be harmful if swallowed.

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

 

 

PACKING

Preserved in light-resistant and well-closed bottles