(R)-3-HYDROXYPYRROLIDINE HYDROCHLORIDE

PRODUCT IDENTIFICATION

CAS NO. 104706-47-0

R-3-HYDROXYPYRROLIDINE HYDROCHLORIDE

EINECS NO.  
FORMULA C4H9NO·HCl
MOL WT. 123.58

H.S. CODE

 
DERIVATION

 

SYNONYMS (R)-3-Pyrrolidinol hydrochloride;

TOXICITY

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

yellow powder

MELTING POINT  
BOILING POINT 108 - 110 C at 8 mm Hg
SPECIFIC GRAVITY 1.045
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

Health: 1; Flammability: 0; Reactivity: 0

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY

Stable under ordinary conditions. Moisture, light sensitive.

GENERAL DESCRIPTION

Pyrrolidine is a part of the structure of amino acids (proline, hydroxyproline and hygrine). Chiral pyrrolidines are used as enantiomeric intermediate in developing the asysmmetric single isomeric drugs including antitumor, anesthetic, antipasmodic, hepatotoxic, antiinflammatory or anti-HIV activity products. They are useful in preparing pyridone carboxylic acid antibacterials, k-receptor opioids, and optically secondary alcohols.
SALES SPECIFICATION

APPEARANCE

yellow powder

CHEMICAL PURITY

99.0% min

OPTICAL ROTATION

-6.5° ~ -7.5° (C=3.5 in MeOH)
TRANSPORTATION
PACKING
 
HAZARD CLASS Not regulated
UN NO.  
OTHER INFORMATION
Hazard Symbols: n/a, Risk Phrases: 36/37/38, Safety Phrases: 26-37/39
The free base gives a positive optical rotation (+5.5° ~ +7.5°, C=3.5 in MeOH)). The hydrochloride form has a negative optical rotation.
PRICE

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