| CAS
NO. |
152305-23-2 |
|
| EINECS
NO. |
|
| FORMULA |
C10H12N2O2 |
| MOL
WT. |
192.22 |
|
H.S.
CODE
|
|
| TOXICITY
|
|
| SYNONYMS |
(s)-4-(4-Aminobenzyl)-1,3-oxazolidin-2-one;
|
|
DERIVATION
|
|
|
CLASSIFICATION
|
|
|
PHYSICAL
AND CHEMICAL PROPERTIES
|
| PHYSICAL
STATE |
white
crystalline powder
|
| MELTING
POINT |
107
- 109 C |
| BOILING
POINT |
|
| SPECIFIC
GRAVITY |
|
| SOLUBILITY
IN WATER |
|
| pH |
|
| VAPOR
DENSITY |
|
|
AUTOIGNITION
|
|
|
NFPA
RATINGS
|
|
|
REFRACTIVE
INDEX
|
|
| FLASH
POINT |
|
| STABILITY |
Stable
under ordinary conditions. |
|
GENERAL
DESCRIPTION
|
| Oxazolidinones, containing not only nitrogen but also oxygen atom in lactam
ring, are used in developing novel drug especially antibiotics of low toxicity
for the host but effective against penicillin-resistant pathogens. Chiral
oxazolidinones are used in the enantioselective synthesis of beta-lactams and
alpha-amino acids. End products can include asysmmetric single isomeric drugs of
antitumor, anesthetic, antipasmodic, hepatotoxic, antiinflammatory or anti-HIV
activity products. Chiral oxazolidinones have wide and effective chiral
applications as chiral auxiliaries, building blocks and ligands. (S)-4-(4-Aminobenzyl)-2-oxazolidinone
may be an intermediate to manufacture antimigraine agent (zolmitriptan). |
| SALES
SPECIFICATION |
|
APPEARANCE
|
white
crystalline powder
|
|
CHEMICAL
PURITY
|
99.0%
min |
|
OPTICAL
PURITY
|
99.0%
min e.e. |
|
LOSS
ON DRYING
|
0.5%
max |
| TRANSPORTATION |
| PACKING |
|
| HAZARD
CLASS |
|
| UN
NO. |
|
| OTHER
INFORMATION |
| Hazard Symbols: , Risk Phrases: ,
Safety Phrases: 24-26 |
| EXAMPLES
OF OXAZOLIDINONE STRUCTURE API
|
|
API
|
CAS
RN.
|
| Furazolidone |
67-45-8 |
| Cycloserine |
68-41-7 |
| Mephenoxalone |
70-07-5 |
| Furaltadone |
139-91-3 |
| Levcycloserine |
339-72-0 |
| Methastyridone |
721-19-7 |
| Metaxalone |
1665-48-1 |
| Pemoline |
2152-34-3 |
| Levofuraltadone |
3795-88-8 |
| Nifuratel |
4936-47-4 |
| Furmethoxadone |
6281-26-1 |
| Fenpipalone |
21820-82-6 |
| Pentizidone sodium |
59831-62-8 |
| Ipenoxazone |
104454-71-9 |
| Befloxatone |
134564-82-2 |
| Panamesine |
139225-22-2 |
| Zolmitriptan |
139264-17-8 |
| Anacetrapinb |
875446-37-0 |
|