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THIOFLAVIN T | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 2390-54-7 |
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| EINECS NO. | 219-228-9 | |
| FORMULA | C17H19ClN2S | |
| MOL WT. | 318.86 | |
| H.S. CODE | ||
| PRICE |
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| TOXICITY | ||
| SYNONYMS | Basic Yellow T; Basic yellow 1; | |
| 3,6-Dimethyl-2-dimethylaminophenylbenzothiazolium chloride; C.I. 49005; C.I. Basic Yellow 1; Citroflavine 8G; Methyldehydrothio-p-toluidine sulfonate; Methylene Yellow N; Methylene Yellow NI; Nankai Basic Flavine 8G; Primoflavine 8G; Purimofurabin 8G; Rhoduline Yellow; Setoflavin T; Setoflavine T; Tannoflavine T; Thioflavin TCN; Thioflavin TG; Thioflavine T; Thioflavine TCN; Thioflavine TCND; 2-(4-(Dimethylamino)phenyl)-3,6-dimethylbenzothiazolium chloride; 2-(p-(Dimethylamino)phenyl)-3,6-dimethylbenzothiazolium chloride; Brilliant Flavine T; | ||
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | yellowish powder | |
| MELTING POINT | ||
| BOILING POINT | ||
| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER | soluble | |
| SOLUBILITY |
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| AUTOIGNITION | ||
| pH | ||
| VAPOR DENSITY | ||
| NFPA RATINGS | Health: 2; Flammability: 1; Reactivity: 0 | |
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REFRACTIVE INDEX |
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| FLASH POINT |
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| STABILITY | Stable under ordinary conditions | |
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GENERAL DESCRIPTION & APPLICATIONS |
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| The IUPAC Name of free base primuline (mole formula: C21H14N3NaO3S3, mole wt.: 475.53893 g/mol) is 2-[2-(4-Aminophenyl)-1,3-benzothiazol-6-yl]-6-methyl-1,3-benzothiazole-7-sulfonic acid which has the featured methylated and sulfonated benzothiazole ring, derived from dehydrothiotoluidine. Commercially available primuline is usually the homogenous mixture of sodium salts, which should have at least three benzothiazole rings. Primuline (Direct Yellow 59), also called thioflavin S , is a fluorescent dye which used to mark or label other compounds with fluorescent tags. The wave length of the emitted light from fluorescent dye is usually longer than that of the incident light. Thioflavin S is the result from the methylation of dehydrothiotoluidine in the presence of sulfuric acid. Thioflavine T (Basic Yellow 1) is 4-(3,6-dimethyl-1,3-benzothiazol-3-ium-2-yl)-N,N-dimethylaniline which is derived from dehydrothiotoluidine by the methylation with hydrochloric acid. They bind to amyloid fibrils and gives a distinct spectral shift; used to diagnose amyloid fibrils, both ex vivo and in vitro. | ||
| SALES SPECIFICATION | ||
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APPEARANCE |
yellowish powder | |
| DYE CONTENT |
75.0% | |
| ABSORPTION | 411 - 414nm | |
| LOSS ON DRYING |
15.0% min | |
| TRANSPORTATION | ||
| PACKING | ||
| HAZARD CLASS | ||
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OTHER INFORMATION |
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