|
BILOBALIDE |
|
(5aR-(3aS*,5aalpha,8beta,8aS*,9alpha,10aalpha))-9-(1,1-Dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-
4H,5aH,9H-furo(2,3-b)furo(3',2':2,3)cyclopenta(1,2-c)furan-2,4,7(3H,8H)-trione;
|
|

|
| PRODUCT
IDENTIFICATION
|
|
CAS
RN
|
33570-04-6 |
|
EINECS
RN |
|
|
FORMULA |
C15H18O8 |
|
MOLE
WEIGHT
|
326.30 |
| PHYSICAL
AND CHEMICAL PROPERTIES
|
|
PHYSICAL
STATE |
white to off-white
powder |
|
MELTING
POINT |
|
|
BOILING
POINT |
|
|
DENSITY
|
|
|
SOLUBILITY
IN WATER |
(Soluble
in alcohol, DMSO) |
|
pH |
|
|
VAPOR
DENSITY |
|
|
REFRACTIVE
INDEX
|
|
|
FLASH
POINT |
|
| STABILITY AND REACTIVITY |
|
STABILITY |
Stable
under normal conditions. |
|
INCOMPATIBLE
MATERIALS
|
Strong
oxidizing agents
|
|
DECOMPOSITION PRODUCTS |
Carbon
oxides
|
|
POLYMERIZATION |
Has not been reported |
|
NFPA
RATINGS
|
Health:
, Flammability: , Reactivity:
|
| SAFETY
|
|
HAZARD
NOTES |
Irritant |
|
EYE
|
May
cause eye irritation.
|
|
SKIN |
May
be harmful if absorbed through skin. May cause skin
irritation.
|
|
INGESTION |
May
be harmful if swallowed.
|
|
INHALATION |
May
be harmful if inhaled. May cause respiratory tract irritation.
|
|
CHRONIC |
|
| TRANSPORT
& REGULATORY INFORMATION
|
|
UN
NO. |
|
| HAZARD CLASS |
|
| PACKING GROUP |
|
| HAZARD SYMBOL
|
XI
|
|
RISK PHRASES |
36/37/38 |
|
SAFETY PHRASES |
22-24/25
|
| EXTERNAL LINKS
& GENERAL
INFORMATION |
|
Ginkgo biloba extract contain specific terpenoids
called ginkgolides (ginkgolide A, ginkgolide B, ginkgolide
C - diterpenes)
and bilobalide (pentanorditerpene). Ginkgolide A (GA) and ginkgolide B (GB) are
the main molecular forms of ginkgolides. These compounds are non-competitive
antagonists of the GABAA and glycine receptors, and
are structurally related to picrotoxin (PTX), also a
non-competitive antagonist of these receptors. These
compounds are thought to bind in the channel of these
receptors. The medical
benefits of GINKGO BILOBA EXTRACT rely primarily on two groups of active
components: the ginkgo flavone glycosides and the terpene lactones. The
ginkgo flavone glycoside designation on GBE labels indicates the carefully
measured balance of bioflavonoids. These bioflavonoids are primarily responsible
for GBE's antioxidant activity and ability to inhibit platelet aggregation.
These two actions may help GBE prevent circulatory diseases such as
atherosclerosis and support the brain and central nervous system. The unique
terpene lactone components found in GBE, known as ginkgolides and bilobalide
typically make up 6% of the extract. They are associated with increased
circulation to the brain and other parts of the body as well as exert a
protective action on nerve cells. Ginkgolides may improve circulation and
inhibit platelet-activating factor. Bilobalide is known to protect the cells of the nervous
system. |
| SALES
SPECIFICATION
|
|
APPEARANCE |
white to off-white
powder |
|
CONTENT
|
98.0%
min
|
| PRICE
INFORMATION
|
 |
|